PCSK7 / PC7

proprotein convertase subtilisin/kexin type 7

PCSK7 / PC7 is a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. It encodes a type 1 membrane bound protease that is expressed in many tissues, including neuroendocrine, liver, gut, and brain. The encoded protein undergoes an initial autocatalytic processing event in the ER and then sorts to the trans-Golgi network through endosomes where a second autocatalytic event takes place and the catalytic activity is acquired. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. It can process proalbumin and is thought to be responsible for the activation of HIV envelope glycoproteins gp160 and gp140. This gene has been implicated in the transcriptional regulation of housekeeping genes and plays a role in the regulation of iron metabolism. A t(11;14)(q23;q32) chromosome translocation associated with B-cell lymphoma occurs between this gene and its inverted counterpart.

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Products

Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

PCSK7 / PC7 (5)

Publications

No (5)

Tag

GST (2)

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (4)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (3)

Purification

Purified (2)

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Human PCSK7 / PC7 Protein (Recombinant GST, N-terminus) (aa434-543) - LS-G61018

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human PCSK7 / PC7 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81533

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

86.1 kDa

Price:

20 µg/$150

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Human PCSK7 / PC7 Protein (Recombinant GST) (Full Length) - LS-G31504

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

90.75 kDa

Price:

10 µg/$479; 25 µg/$670

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Human PCSK7 / PC7 Protein (Recombinant GST) (Full Length) - LS-G31505

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

111.87 kDa

Price:

10 µg/$479; 25 µg/$670

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PCSK7 / PC7 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100373

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

86.1 kDa

Price:

100 µg/$494

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