PCSK4

proprotein convertase subtilisin/kexin type 4

PCSK4 / PC4 is a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to subcellular compartments where a second autocatalytic even takes place and the catalytic activity is acquired. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. The protease is expressed only in the testis, placenta, and ovary. It plays a critical role in fertilization, fetoplacental growth, and embryonic development and processes multiple prohormones including pro-pituitary adenylate cyclase-activating protein and pro-insulin-like growth factor II.

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Products

ELISA Kits (5)

Type

Custom (2)

Sandwich (3)

Target

PCSK4 (5)

Reactivity

Human (2)

Mouse (1)

Rat (2)

Format

96-Well Microplate (1)

96-Well Strip Plate (4)

Publications

No (5)

Sample Type

Cell Lysates (1)

Plasma (2)

Serum (2)

Tissue Homogenates (2)

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Human PCSK4 (Sandwich ELISA) ELISA Kit - LS-F66876

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Rat PCSK4 (Sandwich ELISA) ELISA Kit - LS-F56245

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Rat PCSK4 (Custom) ELISA Kit - LS-F65521

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Price:

1 Plate/$783

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Mouse PCSK4 (Custom) ELISA Kit - LS-F66011

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Price:

1 Plate/$783

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Human PCSK4 (Sandwich ELISA) ELISA Kit - LS-F74150

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$834

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