PCSK4

proprotein convertase subtilisin/kexin type 4

PCSK4 / PC4 is a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to subcellular compartments where a second autocatalytic even takes place and the catalytic activity is acquired. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. The protease is expressed only in the testis, placenta, and ovary. It plays a critical role in fertilization, fetoplacental growth, and embryonic development and processes multiple prohormones including pro-pituitary adenylate cyclase-activating protein and pro-insulin-like growth factor II.

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Products

Antibodies (13)

ELISA Kits (5)

Proteins (3)

Type

Custom (2)

Over-Expression Lysate (2)

Primary (13)

Recombinant (1)

Sandwich (3)

Target

PCSK4 (21)

Reactivity

Human (14)

Mouse (5)

Rat (5)

Bat (3)

Bovine (3)

Chimpanzee (3)

Dog (3)

Monkey (3)

Application

WB (13)

ELISA (7)

Host

rabbit (13)

Isotype

IgG (7)

Clonality

polyclonal pc (13)

Format

96-Well Microplate (1)

96-Well Strip Plate (4)

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (1)

Unconjugated (5)

Epitope

aa168-196 (7)

aa35-84 (4)

aa117-133 (1)

Publications

No (21)

Sample Type

Cell Lysates (1)

Plasma (2)

Serum (2)

Tissue Homogenates (2)

Tag

GST (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human PCSK4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G92773

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

82.6 kDa

Price:

20 µg/$215

Select

PCSK4 Antibody (aa168-196) LS-C323864

Antibody:

PCSK4 Rabbit anti-Human Polyclonal (aa168-196) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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PCSK4 Antibody (aa168-196, Biotin) LS-C238864

Antibody:

PCSK4 Rabbit anti-Human Polyclonal (aa168-196) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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PCSK4 Antibody (aa168-196, FITC) LS-C238865

Antibody:

PCSK4 Rabbit anti-Human Polyclonal (aa168-196) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

PCSK4 Antibody (aa168-196, APC) LS-C238863

Antibody:

PCSK4 Rabbit anti-Human Polyclonal (aa168-196) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

PCSK4 Antibody (aa168-196, PE) LS-C238866

Antibody:

PCSK4 Rabbit anti-Human Polyclonal (aa168-196) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

PCSK4 Antibody (aa168-196, Azide-free, HRP) LS-C248438

Antibody:

PCSK4 Rabbit anti-Human Polyclonal (aa168-196) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

Select

PCSK4 Antibody LS-C754345

Antibody:

PCSK4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$341

Select

PCSK4 Antibody (aa117-133) LS-C313227

Antibody:

PCSK4 Rabbit anti-Mouse Polyclonal (aa117-133) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

PCSK4 Antibody (aa35-84) LS-C112229

Antibody:

PCSK4 Rabbit anti-Human Polyclonal (aa35-84) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

PCSK4 Antibody (aa35-84, HRP) LS-C465316

Antibody:

PCSK4 Rabbit anti-Human Polyclonal (aa35-84) (HRP) Antibody

Reactivity:

Mouse, Dog, Bovine, Rat, Bat, Chimpanzee, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

PCSK4 Antibody (aa35-84, Biotin) LS-C465314

Antibody:

PCSK4 Rabbit anti-Human Polyclonal (aa35-84) (Biotin) Antibody

Reactivity:

Mouse, Dog, Bovine, Rat, Bat, Chimpanzee, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

PCSK4 Antibody (aa35-84, FITC) LS-C465315

Antibody:

PCSK4 Rabbit anti-Human Polyclonal (aa35-84) (FITC) Antibody

Reactivity:

Mouse, Dog, Bovine, Rat, Bat, Chimpanzee, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

PCSK4 Antibody (aa168-196) LS-C163449

Antibody:

PCSK4 Rabbit anti-Human Polyclonal (aa168-196) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

Human PCSK4 (Sandwich ELISA) ELISA Kit - LS-F74150

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$834

Select

Rat PCSK4 (Custom) ELISA Kit - LS-F65521

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Price:

1 Plate/$783

Select

Mouse PCSK4 (Custom) ELISA Kit - LS-F66011

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Price:

1 Plate/$783

Select

Human PCSK4 (Sandwich ELISA) ELISA Kit - LS-F66876

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

Select

Rat PCSK4 (Sandwich ELISA) ELISA Kit - LS-F56245

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Human PCSK4 Protein (Recombinant GST) (Full Length) - LS-G34044

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

52.36 kDa

Price:

10 µg/$479; 25 µg/$670

Select

PCSK4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G112386

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

82.6 kDa

Price:

100 µg/$710

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