PCDHGB6

Protocadherin Gamma Subfamily B, 6

PCDHGB6 is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

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Proteins (2)

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Recombinant (2)

Target

PCDHGB6 (2)

Publications

No (2)

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GST (1)

GST, N-terminus (1)

Species

Human (2)

Source

Wheat Germ Extract (2)

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Purified (1)

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Human PCDHGB6 Protein (Recombinant GST) (Full Length) - LS-G34513

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

116.2 kDa

Price:

10 µg/$479; 25 µg/$670

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Human PCDHGB6 Protein (Recombinant GST, N-terminus) (aa162-269) - LS-G62799

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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