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PCDH11Y / Protocadherin Y belongs to the protocadherin family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing seven cadherin repeats, a transmembrane domain, and a cytoplasmic tail that differs from those of the classical cadherins. This gene is located on the Y chromosome in a block of X/Y homology and is very closely related to its paralog on the X chromosome. The protein is thought to play a role in cell-cell recognition during development of the central nervous system. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene Name: | protocadherin 11 Y-linked |
Synonyms: | PCDH11Y, PCDH22, PCDHY, Protocadherin Y, Protocadherin-PC, Protocadherin prostate cancer, Protocadherin-11 Y-linked, PCDH11, Protocadherin 11 Y-linked, Protocadherin 22, Protocadherin-11, PCDH-PC, PCDH-Y, Protocadherin-22 |
Target Sequences: | NP_116753.1 Q9BZA8 |
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