PCA1 / ALKBH3

alkB, alkylation repair homolog 3 (E. coli)

Dioxygenase that repairs alkylated DNA containing 1-methyladenine (1meA) and 3-methylcytosine (3meC) by oxidative demethylation. Has a strong preference for single-stranded DNA. Able to process alkylated 3mC within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKHB3. May also act on RNA. Requires molecular oxygen, alpha-ketoglutarate and iron.

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Products

Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

PCA1 / ALKBH3 (6)

Publications

No (6)

Tag

GST (1)

His (1)

His-SUMO (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human PCA1 / ALKBH3 Protein (Recombinant His-SUMO) (Full Length) - LS-G21860

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

35.3 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human PCA1 / ALKBH3 Protein (Recombinant GST) (Full Length) - LS-G37039

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

41.03 kDa

Price:

10 µg/$479; 25 µg/$670

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Human PCA1 / ALKBH3 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G72636

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

33.2 kDa

Price:

20 µg/$1,107

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Human PCA1 / ALKBH3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G93114

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

33.2 kDa

Price:

20 µg/$150

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PCA1 / ALKBH3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G102266

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

33.2 kDa

Price:

100 µg/$494

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Human PCA1 / ALKBH3 Protein (Recombinant His) - LS-G1202

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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