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PC5 / PCSK5

proprotein convertase subtilisin/kexin type 5

PC5 / PCSK5 is a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER. It then sorts to the trans-Golgi network where a second autocatalytic event takes place and the catalytic activity is acquired. This encoded protein is widely expressed and one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. It mediates posttranslational endoproteolytic processing for several integrin alpha subunits and is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Alternative splicing results in multiple transcript variants, some of which encode distinct isoforms, including a protease packaged into dense core granules (PC5A) and a type 1 membrane bound protease (PC5B).

Gene Name: proprotein convertase subtilisin/kexin type 5
Family/Subfamily: Protease , Serine S8
Synonyms: PCSK5, HPC6, PC5, PC6A, Prohormone convertase 5, Protease PC6, Proprotein convertase 5, Proprotein convertase 6, SPC6, Subtilisin/kexin type 5, PC6
Target Sequences: NM_006200 NP_006191.2 Q92824

☰ Filters
Antibodies (30)
Proteins (7)
ELISA Kits (1)
Over-Expression Lysate (2)
Primary (30)
Recombinant (5)
Sandwich (1)
PC5 / PCSK5 (38)
Human (27)
Mouse (9)
Rat (5)
Bat (3)
Bovine (3)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Monkey (3)
IHC (3)
IHC-P (1)
WB (21)
ELISA (16)
Peptide-ELISA (1)
rabbit (30)
Product Group
IHCPlus (1)
IgG (17)
polyclonal pc (30)
96-Well Strip Plate (1)
APC (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (5)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (2)
Unconjugated (9)
aa115-454 (8)
aa95-124 (7)
aa792-841 (4)
No (38)
Tissue Homogenates (1)
GST (1)
GST, N-terminus (1)
His (1)
His, N-Terminal (1)
His-SUMO (1)
Myc-DDK (Flag) (2)
Human (4)
Mouse (2)
293T Cells (1)
E. coli (2)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Yeast (1)
Purified (1)
PC5 / PCSK5 Antibody - PCSK5 Antibody western blot of WiDr cell line lysates (35 ug/lane). The PCSK5 antibody detected the PCSK5 protein (arrow).
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PC5 / PCSK5 Rabbit anti-Human Polyclonal (aa95-124) Antibody
Human
Peptide-ELISA, WB
Unconjugated
400 µl/$393
PC5 / PCSK5 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE), at a dilution of 1:50.
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PC5 / PCSK5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
PC5 / PCSK5 Protein - Recombinant Proprotein Convertase Subtilisin/Kexin Type 5 By SDS-PAGE
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E. coli
His, N-Terminal
40.8 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
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PC5 / PCSK5 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
PC5 / PCSK5 Antibody - Immunohistochemistry of paraffin-embedded Human cervical cancer tissue  using PCSK5 Polyclonal Antibody at dilution of 1:50(×200)
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PC5 / PCSK5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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PC5 / PCSK5 Rabbit anti-Human Polyclonal (aa95-124) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
PC5 / PCSK5 Rabbit anti-Human Polyclonal (aa95-124) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
PC5 / PCSK5 Rabbit anti-Human Polyclonal (aa95-124) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
PC5 / PCSK5 Rabbit anti-Human Polyclonal (aa95-124) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
PC5 / PCSK5 Rabbit anti-Human Polyclonal (aa95-124) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
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PC5 / PCSK5 Rabbit anti-Human Polyclonal (aa95-124) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
PC5 / PCSK5 Antibody - IHC image of PCSK5 Antibody diluted at 1:300 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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PC5 / PCSK5 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
Select
PC5 / PCSK5 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
PC5 / PCSK5 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
PC5 / PCSK5 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
Select
PC5 / PCSK5 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
Select
PC5 / PCSK5 Rabbit anti-Mouse Polyclonal (HRP) Antibody
Mouse
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
PC5 / PCSK5 Rabbit anti-Mouse Polyclonal (Biotin) Antibody
Mouse
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
PC5 / PCSK5 Rabbit anti-Mouse Polyclonal (FITC) Antibody
Mouse
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
PC5 / PCSK5 Antibody - PCSK5 / PC5 antibody Western blot of 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PC5 / PCSK5 Rabbit anti-Human Polyclonal (aa792-841) Antibody
Human
WB
Unconjugated
100 µl/$424
PC5 / PCSK5 Antibody - PCSK5 / PC5 antibody Western blot of 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PC5 / PCSK5 Rabbit anti-Human Polyclonal (aa792-841) (HRP) Antibody
Mouse, Dog, Bovine, Rat, Bat, Gibbon, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
PC5 / PCSK5 Antibody - PCSK5 / PC5 antibody Western blot of 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PC5 / PCSK5 Rabbit anti-Human Polyclonal (aa792-841) (Biotin) Antibody
Mouse, Dog, Bovine, Rat, Bat, Gibbon, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
PC5 / PCSK5 Antibody - PCSK5 / PC5 antibody Western blot of 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
PC5 / PCSK5 Rabbit anti-Human Polyclonal (aa792-841) (FITC) Antibody
Mouse, Dog, Bovine, Rat, Bat, Gibbon, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$469
PC5 / PCSK5 Antibody - Western blot of PC5 / PCSK5 antibody.
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PC5 / PCSK5 Rabbit anti-Human Polyclonal (aa115-454) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
PC5 / PCSK5 Antibody - Western blot of PC5 / PCSK5 antibody.
Select
PC5 / PCSK5 Rabbit anti-Human Polyclonal (aa115-454) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
Viewing 1-25 of 38 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).