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PAX7

paired box 7

PAX7 is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene.

Gene Name: paired box 7
Synonyms: PAX7, HUP1, Paired box 7, Paired box gene 7, Paired box homeotic gene 7, Paired box protein Pax-7, RMS2, Paired domain gene 7, PAX7 transcriptional factor, PAX7B
Target Sequences: NM_002584 NP_002575.1 P23759

Publications (2)

1
Parathyroid hormone and parathyroid hormone type-1 receptor accelerate myocyte differentiation. Kimura S, Yoshioka K. Scientific reports. 2014 4:5066. (ELISA; Human) [Full Text Article] [PubMed:24919035] [PMC:PMC4052750]
2
The vestibular system is critical for the changes in muscle and bone induced by hypergravity in mice. Kawao N, Morita H, Obata K, Tamura Y, Okumoto K, Kaji H. Physiological reports. 2016 October;4:pii: e12979. (Human) [Full Text Article] [PubMed:27697847] [PMC:PMC5064136] Related Antibodies: LS-B9285.

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).