PARP3

poly (ADP-ribose) polymerase family, member 3

Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. Binds DNA. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.

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Proteins (8)

Type

Over-Expression Lysate (4)

Recombinant (4)

Target

PARP3 (8)

Publications

No (8)

Tag

GST (1)

His (1)

His-GST (1)

Myc-DDK (Flag) (5)

Species

Human (6)

Source

293T Cells (2)

Baculovirus (1)

HEK 293 Cells (3)

Sf21 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (1)

Biologically Active

Biologically active (1)

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Human PARP3 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G70809

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

59.9 kDa

Price:

20 µg/$1,107

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Human PARP3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88046

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

59.9 kDa

Price:

20 µg/$150

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Human PARP3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88047

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

59.9 kDa

Price:

20 µg/$150

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Human PARP3 Protein (Recombinant His-GST) (Met1-Leu533) - LS-G97747

Source:

Baculovirus

Tag:

His-GST

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

87.8 kDa

Price:

100 µg/$843

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Human PARP3 Protein (Recombinant GST) (Full Length) - LS-G31910

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

84.37 kDa

Price:

10 µg/$479; 25 µg/$670

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PARP3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100564

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

59.9 kDa

Price:

100 µg/$494

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PARP3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G122518

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

59.9 kDa

Price:

100 µg/$494

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Human PARP3 Protein (Recombinant His) (Full Length) - LS-G3990

Source:

Sf21 Cells

Tag:

His

Biological Activity:

Biologically active

Price:

10 µg/$393

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