Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
PARP2 is poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found.
|Gene Name:||poly (ADP-ribose) polymerase 2|
|Synonyms:||PARP2, ADPRT2, ADPRTL2, ADPRTL3, ADPRT-2, ARTD2, HPARP-2, PADPRT-2, PARP-2, Poly(ADP-ribose) synthetase, Poly (ADP-ribose) polymerase 2, Poly[ADP-ribose] synthetase 2, Poly[ADP-ribose] synthase 2, Poly [ADP-ribose] polymerase 2|
|Target Sequences:||NM_005484 NP_005475.2 Q9UGN5|
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