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PARD6A / PAR6

par-6 family cell polarity regulator alpha

Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in the formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.

Gene Name:	par-6 family cell polarity regulator alpha
Synonyms:	PARD6A, PAR-6 alpha, PAR6A, Tax interaction protein 40, Tax-interacting protein 40, PAR-6, PAR-6A, PAR6C, TIP-40, PAR6, PAR6alpha, TAX40
Target Sequences:	NM_016948 NP_058644.1 Q9NPB6

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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