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PARD3

par-3 family cell polarity regulator

Adapter protein involved in asymmetrical cell division and cell polarization processes. Seems to play a central role in the formation of epithelial tight junctions. Targets the phosphatase PTEN to cell junctions. Involved in Schwann cell peripheral myelination (By similarity). Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons.

Gene Name: par-3 family cell polarity regulator
Synonyms: PARD3, Baz, CTCL tumor antigen se2-5, PAR-3, PAR3A, PARD-3, PARD3A, SE2-5LT1, SE2-5T2, PAR3-alpha, PAR3alpha, Bazooka, PAR3, SE2-5L16
Target Sequences: NM_019619 NP_062565.2 Q8TEW0

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Proteins (3)
Over-Expression Lysate (2)
Recombinant (1)
PARD3 (3)
No (3)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
PARD3 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
2 µg/$439
PARD3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
151.2 kDa
20 µg/$215
PARD3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
151.2 kDa
100 µg/$710
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).