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PAP2a / PPAP2A

phosphatidic acid phosphatase type 2A

Broad-specificity phosphohydrolase that dephosphorylates exogenous bioactive glycerolipids and sphingolipids. Catalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG). Pivotal regulator of lysophosphatidic acid (LPA) signaling in the cardiovascular system. Major enzyme responsible of dephosphorylating LPA in platelets, which terminates signaling actions of LPA. May control circulating, and possibly also regulate localized, LPA levels resulting from platelet activation. It has little activity towards ceramide-1-phosphate (C-1-P) and sphingosine-1-phosphate (S-1-P). The relative catalytic efficiency is LPA > PA > S-1-P > C-1-P. It's down-regulation may contribute to the development of colon adenocarcinoma.

Gene Name: phosphatidic acid phosphatase type 2A
Synonyms: PPAP2A, PAP2, PAP2a, PAP2a2, LPP1, LLP1a, PAP-2a, PAP2-alpha, PAP2alpha2, PAPalpha1
Target Sequences: NM_003711 NP_003702.2 O14494

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Products
Antibodies (20)
Primary (20)
PAP2a / PPAP2A (20)
Human (20)
Mouse (10)
Rat (9)
Bat (6)
Bovine (3)
Chicken (3)
Chimpanzee (9)
Dog (6)
Gibbon (6)
Guinea pig (9)
Horse (6)
Monkey (9)
Pig (3)
Xenopus (3)
Zebrafish (3)
IHC (9)
IHC-P (6)
WB (19)
ELISA (2)
Peptide-ELISA (2)
rabbit (18)
mouse (2)
Product Group
IHCPlus (1)
IgG (12)
IgG1 (2)
monoclonal mc (2)
polyclonal pc (18)
OTI1H4 (2)
AP Conjugated (1)
Biotin Conjugated (3)
Carrier-free (1)
FITC Conjugated (3)
HRP Conjugated (3)
Unconjugated (10)
aa136-185 (4)
aa31-80 (4)
aa35-84 (4)
aa247-281 (1)
aa270-304 (1)
No (20)
PAP2a / PPAP2A Antibody - PPAP2A antibody ARP42721_T100-NP_795714-PPAP2A(phosphatidic acid phosphatase type 2A) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PAP2a / PPAP2A Rabbit anti-Human Polyclonal (aa31-80) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$397
PAP2a / PPAP2A Antibody - PPAP2A antibody ARP42721_T100-NP_795714-PPAP2A(phosphatidic acid phosphatase type 2A) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PAP2a / PPAP2A Rabbit anti-Human Polyclonal (aa31-80) (HRP) Antibody
Guinea pig, Rat, Chimpanzee, Gibbon, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$442
PAP2a / PPAP2A Antibody - PPAP2A antibody ARP42721_T100-NP_795714-PPAP2A(phosphatidic acid phosphatase type 2A) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PAP2a / PPAP2A Rabbit anti-Human Polyclonal (aa31-80) (Biotin) Antibody
Guinea pig, Rat, Chimpanzee, Gibbon, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$442
PAP2a / PPAP2A Antibody - PPAP2A antibody ARP42721_T100-NP_795714-PPAP2A(phosphatidic acid phosphatase type 2A) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PAP2a / PPAP2A Rabbit anti-Human Polyclonal (aa31-80) (FITC) Antibody
Guinea pig, Rat, Chimpanzee, Gibbon, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$442
PAP2a / PPAP2A Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
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PAP2a / PPAP2A Rabbit anti-Human Polyclonal (aa270-304) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
200 µl/$460
PAP2a / PPAP2A Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-PPAP2A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
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PAP2a / PPAP2A Mouse anti-Human Monoclonal (OTI1H4) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
PAP2a / PPAP2A Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-PPAP2A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
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PAP2a / PPAP2A Mouse anti-Human Monoclonal (Carrier-free) (OTI1H4) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
PAP2a / PPAP2A Antibody - Immunohistochemistry of paraffin-embedded Human breast cancer using PPAP2A Polyclonal Antibody at dilution of 1:40.
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PAP2a / PPAP2A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
PAP2a / PPAP2A Antibody - Immunohistochemistry of paraffin-embedded Human lung cancer using PPAP2A Polyclonal Antibody at dilution of 1:50.
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PAP2a / PPAP2A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
PAP2a / PPAP2A Antibody - Anti-PPAP2A Antibody at 1:2000 dilution + human kidney lysates Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 32 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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PAP2a / PPAP2A Rabbit anti-Human Polyclonal (aa247-281) Antibody
Human
Peptide-ELISA, WB
Unconjugated
400 µl/$393
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PAP2a / PPAP2A Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$466
PAP2a / PPAP2A Antibody - PPAP2A antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PAP2a / PPAP2A Rabbit anti-Human Polyclonal (aa35-84) Antibody
Human
WB
Unconjugated
100 µl/$424
PAP2a / PPAP2A Antibody - PPAP2A antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PAP2a / PPAP2A Rabbit anti-Human Polyclonal (aa35-84) (HRP) Antibody
Mouse, Dog, Guinea pig, Horse, Bat, Human, Monkey, Chimpanzee
WB
HRP Conjugated
100 µl/$469
PAP2a / PPAP2A Antibody - PPAP2A antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PAP2a / PPAP2A Rabbit anti-Human Polyclonal (aa35-84) (Biotin) Antibody
Mouse, Dog, Guinea pig, Horse, Bat, Human, Monkey, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
PAP2a / PPAP2A Antibody - PPAP2A antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PAP2a / PPAP2A Rabbit anti-Human Polyclonal (aa35-84) (FITC) Antibody
Mouse, Dog, Guinea pig, Horse, Bat, Human, Monkey, Chimpanzee
WB
FITC Conjugated
100 µl/$469
PAP2a / PPAP2A Antibody - PPAP2A antibody ARP42146_T100-NP_795714-PPAP2A(phosphatidic acid phosphatase type 2A) Antibody Western blot of Jurkat lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PAP2a / PPAP2A Rabbit anti-Human Polyclonal (aa136-185) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$397
PAP2a / PPAP2A Antibody - PPAP2A antibody ARP42146_T100-NP_795714-PPAP2A(phosphatidic acid phosphatase type 2A) Antibody Western blot of Jurkat lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PAP2a / PPAP2A Rabbit anti-Human Polyclonal (aa136-185) (HRP) Antibody
Xenopus, Chicken, Zebrafish, Mouse, Dog, Guinea pig, Bovine, Bat, Pig, Horse, Rat, Gibbon, Human, Monkey, Chimpanzee
WB
HRP Conjugated
100 µl/$442
PAP2a / PPAP2A Antibody - PPAP2A antibody ARP42146_T100-NP_795714-PPAP2A(phosphatidic acid phosphatase type 2A) Antibody Western blot of Jurkat lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PAP2a / PPAP2A Rabbit anti-Human Polyclonal (aa136-185) (Biotin) Antibody
Xenopus, Chicken, Zebrafish, Mouse, Dog, Guinea pig, Bovine, Bat, Pig, Horse, Rat, Gibbon, Human, Monkey, Chimpanzee
WB
Biotin Conjugated
100 µl/$442
PAP2a / PPAP2A Antibody - PPAP2A antibody ARP42146_T100-NP_795714-PPAP2A(phosphatidic acid phosphatase type 2A) Antibody Western blot of Jurkat lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PAP2a / PPAP2A Rabbit anti-Human Polyclonal (aa136-185) (FITC) Antibody
Xenopus, Chicken, Zebrafish, Mouse, Dog, Guinea pig, Bovine, Bat, Pig, Horse, Rat, Gibbon, Human, Monkey, Chimpanzee
WB
FITC Conjugated
100 µl/$442
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PAP2a / PPAP2A Rabbit anti-Human Polyclonal (AP) Antibody
Mouse, Rat, Human
WB
AP Conjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Viewing 1-20 of 20 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).