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PANX1 / Pannexin 1

pannexin 1

PANX1 / Pannexin 1 belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties.

Gene Name:	pannexin 1
Synonyms:	PANX1, Pannexin-1, UNQ2529, Pannexin 1, PX1, Innexin, MRS1
Target Sequences:	NM_015368 NP_056183.2 Q96RD7

Publications (1)

Sarcoma Family Kinase-Dependent Pannexin-1 Activation after Cortical Spreading Depression is Mediated by NR2A-Containing Receptors. Fan Bu, Lingdi Nie, John P Quinn, Minyan Wang. International journal of molecular sciences. 2020 Feb;21:1269. [Full Text Article] [PubMed:32070042] [PMC:PMC7072958]

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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