PAK7/PAK5

p21 protein (Cdc42/Rac)-activated kinase 7

PAK7 is a serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, proliferation or cell survival. Activation by various effectors including growth factor receptors or active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates the proto-oncogene RAF1 and stimulates its kinase activity. Promotes cell survival by phosphorylating the BCL2 antagonist of cell death BAD. Phosphorylates CTNND1, probably to regulate cytoskeletal organization and cell morphology. Keeps microtubules stable through MARK2 inhibition and destabilizes the F-actin network leading to the disappearance of stress fibers and focal adhesions.

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Products

Proteins (6)

Type

Over-Expression Lysate (4)

Recombinant (2)

Target

PAK7/PAK5 (6)

Publications

No (6)

Tag

6His, N-terminus (1)

Myc-DDK (Flag) (5)

Species

Human (4)

Source

293T Cells (2)

Baculovirus (1)

HEK 293 Cells (3)

Purification

Purified (1)

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Human PAK7/PAK5 Protein (Recombinant 6His, N-terminus) (aa1-293) - LS-G55986

Source:

Baculovirus

Tag:

6His, N-terminus

Price:

100 µg/$1,164; 20 µg/$475; 1 mg/$2,187

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Human PAK7/PAK5 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69534

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

80.6 kDa

Price:

20 µg/$1,107

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Human PAK7/PAK5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84888

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

80.6 kDa

Price:

20 µg/$215

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Human PAK7/PAK5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84887

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

80.6 kDa

Price:

20 µg/$150

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PAK7/PAK5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G102491

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

80.6 kDa

Price:

100 µg/$710

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PAK7/PAK5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G111219

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

80.6 kDa

Price:

100 µg/$494

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