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PAEP / Glycodelin / GdF

progestagen-associated endometrial protein

PAEP / Glycodelin / GdF is a member of the kernel lipocalin superfamily whose members share relatively low sequence similarity but have highly conserved exon/intron structure and three-dimensional protein folding. Most lipocalins are clustered on the long arm of chromosome 9. The encoded glycoprotein has been previously referred to as pregnancy-associated endometrial alpha-2-globulin, placental protein 14, and glycodelin, but has been officially named progestagen-associated endometrial protein. Three distinct forms, with identical protein backbones but different glycosylation profiles, are found in amniotic fluid, follicular fluid and seminal plasma of the reproductive system. These glycoproteins have distinct and essential roles in regulating a uterine environment suitable for pregnancy and in the timing and occurrence of the appropriate sequence of events in the fertilization process. A number of alternatively spliced transcript variants have been observed at this locus, but the full-length nature of only two, each encoding the same protein, has been determined.

Gene Name: progestagen-associated endometrial protein
Synonyms: PAEP, GD, GdF, Glycodelin, Glycodelin-S, Glycodelin-A, Glycodelin-F, PP14, Alpha uterine protein, Placental protein 14, GdS, PAEG, PEP
Target Sequences: NM_001018049 NP_001018059.1 P09466

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Proteins (8)
Over-Expression Lysate (2)
Recombinant (6)
PAEP / Glycodelin / GdF (8)
No (8)
10His, N-terminus + Myc, C-terminus (2)
GST (1)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (3)
Human (6)
E. coli (2)
HEK 293 Cells (3)
Mammalian Cells (1)
Wheat Germ Extract (2)
Purified (4)
PAEP / Glycodelin / GdF Protein - Purified recombinant protein PAEP was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
18.8 kDa
20 µg/$1,107
PAEP / Glycodelin / GdF Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
PAEP / Glycodelin / GdF Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
10His, N-terminus + Myc, C-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
PAEP / Glycodelin / GdF Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Mammalian Cells
10His, N-terminus + Myc, C-terminus
100 µg/$1,266; 20 µg/$506; 1 mg/$4,627
PAEP / Glycodelin / GdF Protein - 12.5% SDS-PAGE of human PAEP stained with Coomassie Blue
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Wheat Germ Extract
GST
47 kDa
10 µg/$479; 25 µg/$670
PAEP / Glycodelin / GdF Protein
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E. coli
His
50 µg/$411; 250 µg/$985; 10 µg/$276
PAEP / Glycodelin / GdF Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
20.62 kDa
100 µg/$494
PAEP / Glycodelin / GdF Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
20.62 kDa
100 µg/$494
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).