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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PAEL Receptor / GPR37

G protein-coupled receptor 37 (endothelin receptor type B-like)

GPR37 is an Orphan-A GPCR with an unknown ligand. GPR37 was recently identified as the PAEL receptor, a Parkin substrate involved in autosomal recessive juvenile Parkinson's (PDJ) disease. The PAEL receptor becomes unfolded, insoluble, and ubiquitinated when overexpressed, leading to unfolded protein-induced cell death. When the PAEL receptor is ubiquitinated by Parkin, it gets degraded, resulting in the suppression of cell death. The insoluble form of the PAEL receptor accumulates in the brains of PDJ patients and may cause selective neuronal death.

Gene Name: G protein-coupled receptor 37 (endothelin receptor type B-like)
Family/Subfamily: GPCR , Orphan-A
Synonyms: GPR37, EDNRBL, ETBR-LP-1, Gpcr/cns1, HET(B)R-LP, Het-b-r-lp, PAELR, Pael receptor
Target Sequences: NM_005302 NP_005293.1 O15354

Filtered by: None
Target
PAEL Receptor / GPR37 (40)
Reactivity
Human (40)
Mouse (4)
Rat (4)
Bovine (4)
Chicken (4)
Chimpanzee (3)
Dog (4)
Gibbon (3)
Horse (4)
Monkey (4)
Orangutan (3)
Rabbit (4)
Xenopus (4)
Application
IHC (30)
IHC-P (30)
WB (11)
Flo (1)
ELISA (10)
Peptide-ELISA (2)
Host
rabbit (39)
mouse (1)
Isotype
IgG (5)
IgG2a (1)
Clonality
monoclonal mc (1)
polyclonal pc (39)
Format
AP Conjugated (4)
APC Conjugated (4)
Azide-free (4)
Biotin Conjugated (5)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (4)
Unconjugated (13)
Epitope
N-Terminus (28)
aa468-517 (4)
180-260 aa, Internal (1)
aa199-248 (1)
aa211-260 (1)
aa217-246 (1)
aa97-126 (1)
Publications
No (40)
Showing 1-25 of 40 results

IHC-plus™ PAEL Receptor / GPR37 Antibody (N-Terminus) LS-A129
Rabbit Polyclonal to Human PAEL Receptor / GPR37
Human
IHC, IHC-P
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-PAEL Receptor / GPR37 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PAEL Receptor / GPR37 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ PAEL Receptor / GPR37 Antibody (N-Terminus, Biotin) LS-A100795
Rabbit Polyclonal to Human PAEL Receptor / GPR37
Human
IHC, IHC-P
Biotin Conjugated
100µl  $650.00
Anti-PAEL Receptor / GPR37 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PAEL Receptor / GPR37 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ PAEL Receptor / GPR37 Antibody (N-Terminus, FITC) LS-A100796
Rabbit Polyclonal to Human PAEL Receptor / GPR37
Human
IHC, IHC-P
FITC Conjugated
100µl  $650.00
Anti-PAEL Receptor / GPR37 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PAEL Receptor / GPR37 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ PAEL Receptor / GPR37 Antibody (N-Terminus, PE) LS-A100798
Rabbit Polyclonal to Human PAEL Receptor / GPR37
Human
IHC, IHC-P
PE Conjugated
100µl  $650.00
Anti-PAEL Receptor / GPR37 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PAEL Receptor / GPR37 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ PAEL Receptor / GPR37 Antibody (N-Terminus, APC) LS-A100794
Rabbit Polyclonal to Human PAEL Receptor / GPR37
Human
IHC, IHC-P
APC Conjugated
100µl  $650.00
Anti-PAEL Receptor / GPR37 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PAEL Receptor / GPR37 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ PAEL Receptor / GPR37 Antibody (N-Terminus, Azide-free, HRP) LS-A100797
Rabbit Polyclonal to Human PAEL Receptor / GPR37
Human
IHC, IHC-P
HRP Conjugated, Azide-free
100µl  $650.00
Anti-PAEL Receptor / GPR37 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PAEL Receptor / GPR37 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ PAEL Receptor / GPR37 Antibody (N-Terminus, AP) LS-A100793
Rabbit Polyclonal to Human PAEL Receptor / GPR37
Human
IHC, IHC-P
AP Conjugated
100µl  $650.00
Anti-PAEL Receptor / GPR37 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PAEL Receptor / GPR37 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ PAEL Receptor / GPR37 Antibody (N-Terminus) LS-A127
Rabbit Polyclonal to Human PAEL Receptor / GPR37
Human
ELISA, IHC, IHC-P
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-GPR37 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ PAEL Receptor / GPR37 Antibody (N-Terminus, Biotin) LS-A100741
Rabbit Polyclonal to Human PAEL Receptor / GPR37
Human
ELISA, IHC, IHC-P
Biotin Conjugated
100µl  $650.00
Anti-GPR37 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ PAEL Receptor / GPR37 Antibody (N-Terminus, FITC) LS-A100742
Rabbit Polyclonal to Human PAEL Receptor / GPR37
Human
ELISA, IHC, IHC-P
FITC Conjugated
100µl  $650.00
Anti-GPR37 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ PAEL Receptor / GPR37 Antibody (N-Terminus, Azide-free, HRP) LS-A100743
Rabbit Polyclonal to Human PAEL Receptor / GPR37
Human
ELISA, IHC, IHC-P
HRP Conjugated, Azide-free
100µl  $650.00
Anti-GPR37 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ PAEL Receptor / GPR37 Antibody (N-Terminus, APC) LS-A100740
Rabbit Polyclonal to Human PAEL Receptor / GPR37
Human
ELISA, IHC, IHC-P
APC Conjugated
100µl  $650.00
Anti-GPR37 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ PAEL Receptor / GPR37 Antibody (N-Terminus, AP) LS-A100739
Rabbit Polyclonal to Human PAEL Receptor / GPR37
Human
ELISA, IHC, IHC-P
AP Conjugated
100µl  $650.00
Anti-GPR37 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ PAEL Receptor / GPR37 Antibody (N-Terminus, PE) LS-A100744
Rabbit Polyclonal to Human PAEL Receptor / GPR37
Human
ELISA, IHC, IHC-P
PE Conjugated
100µl  $650.00
Anti-GPR37 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ PAEL Receptor / GPR37 Antibody (N-Terminus) LS-A4564
Rabbit Polyclonal to Human PAEL Receptor / GPR37
Human
IHC, IHC-P
Unconjugated
50µg 1mg/ml  $425.00
Anti-GPR37 antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

PAEL Receptor / GPR37 Antibody (aa97-126) LS-C99200
Rabbit Polyclonal to Human PAEL Receptor / GPR37
Human
IHC, IHC-P, WB
Unconjugated
400µl  $325.00
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Western blot of anti-Pael-R (GPR37) antibody in mouse brain tissue lysate. Pael-R (GPR37) (arrow) was detected using the purified antibody.

PAEL Receptor / GPR37 Antibody LS-C74025
Mouse Monoclonal (IgG2a) to Human PAEL Receptor / GPR37
Human
Flo
Unconjugated
100µg  $650.00

PAEL Receptor / GPR37 Antibody (aa468-517) LS-C151730
Rabbit Polyclonal to Human PAEL Receptor / GPR37
Xenopus, Chicken, Bovine, Horse, Rabbit, Dog, Human, Monkey
WB
Unconjugated
100µl 0.5mg/ml  $365.00
PAEL Receptor / GPR37 antibody Western Blot of Fetal Heart.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

IHC-plus™ PAEL Receptor / GPR37 Antibody (N-Terminus) LS-A131
Rabbit Polyclonal to Human PAEL Receptor / GPR37
Human
IHC, IHC-P
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-PAEL Receptor / GPR37 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PAEL Receptor / GPR37 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ PAEL Receptor / GPR37 Antibody (N-Terminus, Biotin) LS-A100861
Rabbit Polyclonal to Human PAEL Receptor / GPR37
Human
IHC, IHC-P
Biotin Conjugated
100µl  $650.00
Anti-PAEL Receptor / GPR37 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PAEL Receptor / GPR37 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ PAEL Receptor / GPR37 Antibody (N-Terminus, FITC) LS-A100862
Rabbit Polyclonal to Human PAEL Receptor / GPR37
Human
IHC, IHC-P
FITC Conjugated
100µl  $650.00
Anti-PAEL Receptor / GPR37 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PAEL Receptor / GPR37 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ PAEL Receptor / GPR37 Antibody (N-Terminus, AP) LS-A100859
Rabbit Polyclonal to Human PAEL Receptor / GPR37
Human
IHC, IHC-P
AP Conjugated
100µl  $650.00
Anti-PAEL Receptor / GPR37 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PAEL Receptor / GPR37 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ PAEL Receptor / GPR37 Antibody (N-Terminus, APC) LS-A100860
Rabbit Polyclonal to Human PAEL Receptor / GPR37
Human
IHC, IHC-P
APC Conjugated
100µl  $650.00
Anti-PAEL Receptor / GPR37 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PAEL Receptor / GPR37 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ PAEL Receptor / GPR37 Antibody (N-Terminus, PE) LS-A100864
Rabbit Polyclonal to Human PAEL Receptor / GPR37
Human
IHC, IHC-P
PE Conjugated
100µl  $650.00
Anti-PAEL Receptor / GPR37 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PAEL Receptor / GPR37 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ PAEL Receptor / GPR37 Antibody (N-Terminus, Azide-free, HRP) LS-A100863
Rabbit Polyclonal to Human PAEL Receptor / GPR37
Human
IHC, IHC-P
HRP Conjugated, Azide-free
100µl  $650.00
Anti-PAEL Receptor / GPR37 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PAEL Receptor / GPR37 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Showing 1-25 of 40 results

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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).