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PADI3

peptidyl arginine deiminase, type III

PADI3 is a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type III enzyme modulates hair structural proteins, such as filaggrin in the hair follicle and trichohyalin in the inner root sheath, during hair follicle formation. Together with the type I enzyme, this enzyme may also play a role in terminal differentiation of the epidermis. This gene exists in a cluster with four other paralogous genes.

Gene Name: peptidyl arginine deiminase, type III
Synonyms: PADI3, PAD3, PDI3, Peptidylarginine deiminase III
Target Sequences: NM_016233 NP_057317.2 Q9ULW8

Publications (1)

1
Palmitoyl Acyltransferase Activity of ZDHHC13 Regulates Skin Barrier Development Partly by Controlling PADi3 and TGM1 Protein Stability. Li-Ying Chen, Kuo-Ray Lin, Yi-Ju Chen, Yun-Jung Chiang, Kun-Chin Ho, Li-Fen Shen, I-Wen Song, Kai-Ming Liu, Hsin-Fang Yang-Yen, Yu-Ju Chen, Yuan-Tsong Chen, Fu-Tong Liu, Jeffrey J Y Yen. The Journal of investigative dermatology. 2020 May;140:959-970.e3. [Full Text Article] [PubMed:31669413] Related Antibodies: LS-C153534.

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PADI3 ELISA Kit
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Development Kit
Antibody Pair and Standard
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Saliva, Tissue Homogenates
500 Wells/$1,276; 1000 Wells/$1,903
PADI3 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$834
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).