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PADI1

peptidyl arginine deiminase, type I

PADI1 is a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type I enzyme is involved in the late stages of epidermal differentiation, where it deiminates filaggrin and keratin K1, which maintains hydration of the stratum corneum, and hence the cutaneous barrier function. This enzyme may also play a role in hair follicle formation. This gene exists in a cluster with four other paralogous genes.

Gene Name: peptidyl arginine deiminase, type I
Synonyms: PADI1, HPAD-colony 10, PAD1, HPAD10, PDI, Peptidylarginine deiminase I
Target Sequences: NM_013358 NP_037490.2 Q9ULC6

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Products
Proteins (7)
Over-Expression Lysate (2)
Recombinant (5)
PADI1 (7)
No (7)
GST, N-terminus (1)
His (2)
His-T7, N-terminus (1)
Myc-DDK (Flag) (3)
Human (6)
293T Cells (1)
E. coli (2)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Yeast (1)
Purified (1)
PADI1 Protein - Recombinant Peptidyl Arginine Deiminase Type I (PADI1) by SDS-PAGE
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E. coli
His-T7, N-terminus
33.1kDa
10 µg/$271; 50 µg/$382; 200 µg/$762; 100 µg/$610; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998
PADI1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
PADI1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
74.5 kDa
100 µg/$710
PADI1 Protein
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E. coli
His
78.8 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
PADI1 Protein
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Yeast
His
76.67 kD
100 µg/$446; 20 µg/$336; 1 mg/$1,460
PADI1 Protein - Purified recombinant protein PADI1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
74.5 kDa
20 µg/$1,107
PADI1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
74.5 kDa
20 µg/$215
Viewing 1-7 of 7 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).