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PAD2 / PADI2

peptidyl arginine deiminase, type II

PAD2 / PADI2 is a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes.

Gene Name: peptidyl arginine deiminase, type II
Synonyms: PADI2, PAD-H19, PDI2, PAD2, Protein arginine deiminase, KIAA0994, Peptidylarginine deiminase II
Target Sequences: AB023211 BAA76838.1 Q9Y2J8

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Products
Proteins (7)
Over-Expression Lysate (2)
Recombinant (5)
PAD2 / PADI2 (7)
No (7)
GST, N-terminus (1)
His (1)
His-GST (1)
His-SUMO (1)
Myc-DDK (Flag) (3)
Human (6)
293T Cells (1)
E. coli (2)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Yeast (1)
PAD2 / PADI2 Protein - Recombinant Peptidyl Arginine Deimina Type II By SDS-PAGE
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E. coli
His-GST
63.9 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
PAD2 / PADI2 Protein
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Yeast
His
77.5 kD
1 mg/$1,607; 100 µg/$469; 20 µg/$349
PAD2 / PADI2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
75.4 kDa
100 µg/$710
PAD2 / PADI2 Protein
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E. coli
His-SUMO
91.5 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
PAD2 / PADI2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
PAD2 / PADI2 Protein - Purified recombinant protein PADI2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
75.4 kDa
20 µg/$1,107
PAD2 / PADI2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
75.4 kDa
20 µg/$215
Viewing 1-7 of 7 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).