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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PACSIN2

protein kinase C and casein kinase substrate in neurons 2

Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle-mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus. May also play a role in the formation of caveolae at the cell membrane. Recruits DNM2 to caveolae, and thereby plays a role in caveola-mediated endocytosis.

Gene Name: protein kinase C and casein kinase substrate in neurons 2
Synonyms: PACSIN2, SDPII, Syndapin II
Target Sequences: NM_007229 NP_009160.2 Q9UNF0

Publications (1)

1
The F-BAR domain protein PACSIN2 associates with Rac1 and regulates cell spreading and migration. de Kreuk BJ, Nethe M, Fernandez-Borja M, Anthony EC, Hensbergen PJ, Deelder AM, Plomann M, Hordijk PL. Journal of cell science. 2011 124:2375-88. [PubMed:21693584] Related Antibodies: LS-C101183.

Filtered By: None
Target
PACSIN2 (19)
Reactivity
Human (19)
Mouse (14)
Rat (3)
Bovine (1)
Chicken (1)
Dog (1)
Xenopus (1)
Application
IHC (17)
IHC-P (5)
WB (17)
ELISA (14)
ICC (6)
IF (3)
IP (1)
Host
rabbit (17)
mouse (2)
Isotype
IgG (14)
IgG1,k (1)
IgG2a,k (1)
Clonality
monoclonal mc (2)
polyclonal pc (17)
Clone
1735CT116.76.60 (1)
3D6 (1)
Format
AP Conjugated (1)
APC Conjugated (1)
Azide-free (2)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (13)
Epitope
aa342-371 (8)
aa400-450 (1)
Publications
No (18)
Yes (1)
Showing 1-19 of 19 results

PACSIN2 Antibody (aa400-450) IHC-plus™ LS-B1787
Rabbit Polyclonal to Human PACSIN2
Xenopus, Chicken, Bovine, Mouse, Dog, Rat, Human
IHC IHC-P WB
Unconjugated
50µg 0.5mg/ml  $425.00
Anti-PACSIN2 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Western blot of PACSIN2 in human brain lysate in the 1) absence and 2) presence of immunizing peptide, 3) mouse brain lysate and 4) rat brain lysate using antibody at 0.05 ug/ml.
Anti-PACSIN2 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Western blot of PACSIN2 in human brain lysate in the 1) absence and 2) presence of immunizing peptide, 3) mouse brain lysate and 4) rat brain lysate using antibody at 0.05 ug/ml.

PACSIN2 Antibody (aa342-371) LS-C101183
Publications (1)
Publications (1)
Rabbit Polyclonal to Human PACSIN2
Mouse, Human
IF IHC IHC-P WB
Unconjugated
400µl  $305.00
Immunohistochemical of paraffin-embedded H.stomach section using PACSIN2 Antibody. Antibody was diluted at 1:100 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Immunohistochemical of paraffin-embedded H.stomach section using PACSIN2 Antibody. Antibody was diluted at 1:100 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

PACSIN2 Antibody (aa342-371, Biotin) LS-C226085
Rabbit Polyclonal (IgG) to Human PACSIN2
Mouse, Human
ELISA ICC IHC WB
Biotin Conjugated
200µl  $680.00

PACSIN2 Antibody (aa342-371, FITC) LS-C226086
Rabbit Polyclonal (IgG) to Human PACSIN2
Mouse, Human
ELISA ICC IHC WB
FITC Conjugated
200µl  $680.00

PACSIN2 Antibody (aa342-371, Azide-free) LS-C328127
Rabbit Polyclonal (IgG) to Human PACSIN2
Mouse, Human
ELISA IF IHC WB
Unconjugated, Azide-free
200µl 0.25mg/ml  $530.00

PACSIN2 Antibody (aa342-371, AP) LS-C226082
Rabbit Polyclonal (IgG) to Human PACSIN2
Mouse, Human
ELISA ICC IHC WB
AP Conjugated
200µl  $680.00

PACSIN2 Antibody (aa342-371, APC) LS-C226084
Rabbit Polyclonal (IgG) to Human PACSIN2
Mouse, Human
ELISA ICC IHC WB
APC Conjugated
200µl  $680.00

PACSIN2 Antibody (aa342-371, Azide-free, HRP) LS-C226087
Rabbit Polyclonal (IgG) to Human PACSIN2
Mouse, Human
ELISA ICC IHC WB
HRP Conjugated, Azide-free
200µl  $680.00

PACSIN2 Antibody (aa342-371, PE) LS-C226088
Rabbit Polyclonal (IgG) to Human PACSIN2
Mouse, Human
ELISA ICC IHC WB
PE Conjugated
200µl  $680.00

PACSIN2 Antibody LS-C676217
Rabbit Polyclonal (IgG) to Human PACSIN2
Human
ELISA IHC IHC-P WB
Unconjugated
50µl  $235.00; 100µl  $285.00
Immunohistochemistry of paraffin-embedded human gastric cancer at dilution 1:100
Immunohistochemistry of paraffin-embedded human pancreatic tissue at dilution 1:100
Immunohistochemistry of paraffin-embedded human gastric cancer at dilution 1:100
Immunohistochemistry of paraffin-embedded human pancreatic tissue at dilution 1:100

PACSIN2 Antibody LS-C676218
Rabbit Polyclonal (IgG) to Human PACSIN2
Human
ELISA IHC IHC-P WB
Unconjugated
50µl  $235.00; 100µl  $285.00
Immunohistochemistry of paraffin-embedded human gastric cancer at dilution 1:100
Immunohistochemistry of paraffin-embedded human pancreatic tissue at dilution 1:100
Immunohistochemistry of paraffin-embedded human gastric cancer at dilution 1:100
Immunohistochemistry of paraffin-embedded human pancreatic tissue at dilution 1:100

PACSIN2 Antibody (clone 3D6) LS-C134035
Mouse Monoclonal [clone 3D6] (IgG2a,k) to Human PACSIN2
Human
ELISA IHC IHC-P WB
Unconjugated
100µg  $355.00
Immunoperoxidase of monoclonal antibody to PACSIN2 on formalin-fixed paraffin-embedded human kidney. [antibody concentration 3 ug/ml]
Detection limit for recombinant GST tagged PACSIN2 is 0.1 ng/ml as a capture antibody.
Immunoperoxidase of monoclonal antibody to PACSIN2 on formalin-fixed paraffin-embedded human kidney. [antibody concentration 3 ug/ml]
Detection limit for recombinant GST tagged PACSIN2 is 0.1 ng/ml as a capture antibody.

PACSIN2 Antibody LS-C667425
Rabbit Polyclonal (IgG) to Human PACSIN2
Human
ELISA IHC IP WB
Unconjugated
100µg  $355.00

PACSIN2 Antibody LS-C497959
Rabbit Polyclonal (IgG) to Human PACSIN2
Mouse, Human
IF IHC WB
Unconjugated
100µl  $295.00; 200µl  $385.00
Western blot analysis of extracts of various cell lines.
Western blot analysis of extracts of various cell lines.

PACSIN2 Antibody LS-C401370
Rabbit Polyclonal (IgG) to Human PACSIN2
Mouse, Rat, Human
ELISA IHC
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human colon cancer using PACSIN2 Polyclonal Antibody at dilution of 1:20.
Immunohistochemistry of Human colon cancer using PACSIN2 Polyclonal Antibody at dilution of 1:20.
Immunohistochemistry of Human colon cancer using PACSIN2 Polyclonal Antibody at dilution of 1:20.
Immunohistochemistry of Human colon cancer using PACSIN2 Polyclonal Antibody at dilution of 1:20.

PACSIN2 Antibody LS-C409330
Rabbit Polyclonal (IgG) to Human PACSIN2
Mouse, Human
IHC WB
Unconjugated
50µl  $255.00; 100µl  $315.00; 200µl  $425.00
Western blot analysis of extracts of various cells.
Western blot analysis of extracts of various cells.

PACSIN2 Antibody LS-C404649
Rabbit Polyclonal (IgG) to Human PACSIN2
Mouse, Rat, Human
ELISA IHC
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human esophagus cancer using PACSIN2 Polyclonal Antibody at dilution of 1:20.
Immunohistochemistry of Human esophagus cancer using PACSIN2 Polyclonal Antibody at dilution of 1:20.
Immunohistochemistry of Human esophagus cancer using PACSIN2 Polyclonal Antibody at dilution of 1:20.
Immunohistochemistry of Human esophagus cancer using PACSIN2 Polyclonal Antibody at dilution of 1:20.

PACSIN2 Antibody (clone 1735CT116.76.60) LS-C757753
Mouse Monoclonal [clone 1735CT116.76.60] (IgG1,k) to Human PACSIN2
Mouse, Human
ELISA WB
Unconjugated
50µl  $215.00; 200µl  $325.00
All lanes: Anti-PACSIN2 Antibody at 1:2000 dilution Lane 1: Daudi whole cell lysate Lane 2: HL-60 whole cell lysate Lane 3: human brain lysate Lane 4: mouse brain lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size: 56 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
All lanes: Anti-PACSIN2 Antibody at 1:2000 dilution Lane 1: Daudi whole cell lysate Lane 2: HL-60 whole cell lysate Lane 3: human brain lysate Lane 4: mouse brain lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size: 56 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

PACSIN2 Antibody LS-C482885
Rabbit Polyclonal to Human PACSIN2
Human
WB
Unconjugated
50µl 1mg/ml  $255.00; 100µl 1mg/ml  $295.00; 200µl 1mg/ml  $375.00
Western blot analysis of Syndapin-2 expression in HepG2 (A); mouse lung (B); mouse heart (C) whole cell lysates.
Western blot analysis of Syndapin-2 expression in HepG2 (A); mouse lung (B); mouse heart (C) whole cell lysates.
Showing 1-19 of 19 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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