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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PABPC4

poly(A) binding protein, cytoplasmic 4 (inducible form)

Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: poly(A) binding protein, cytoplasmic 4 (inducible form)
Synonyms: PABPC4, Activated-platelet protein 1, APP-1, APP1, IPABP, Poly(A)-binding protein 4, PABP-4, PABP4
Target Sequences: NM_003819 NP_003810.1 Q13310

Filtered By: None
Target
PABPC4 (24)
Reactivity
Human (24)
Mouse (8)
Rat (11)
Bat (4)
Bovine (3)
Chimpanzee (6)
Dog (7)
Gibbon (6)
Guinea pig (7)
Horse (10)
Monkey (8)
Pig (3)
Rabbit (4)
Application
IHC (12)
IHC-P (9)
WB (23)
ELISA (8)
IF (4)
IP (3)
Host
rabbit (24)
Isotype
IgG (21)
Clonality
polyclonal pc (24)
Format
AP Conjugated (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (12)
Epitope
aa219-247 (8)
aa181-230 (4)
aa432-481 (4)
aa525-575 (2)
Internal (1)
aa594-644 (1)
Publications
No (24)
Showing 1-24 of 24 results

PABPC4 Antibody LS-C667426
Rabbit Polyclonal (IgG) to Human PABPC4
Human
ELISA IF IHC IP WB
Unconjugated
100µg  $335.00

PABPC4 Antibody (aa594-644) LS-C288262
Rabbit Polyclonal (IgG) to Human PABPC4
Mouse, Dog, Guinea pig, Bovine, Pig, Human
IF IHC IHC-P IP WB
Unconjugated
100µl 0.2mg/ml  $395.00
Detection of Human PABP4 by Immunohistochemistry. Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti-PABP4 used at a dilution of 1:200 (1 ug/ml). Detection: DAB.
Detection of Human PABP4 by Immunohistochemistry. Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti-PABP4 used at a dilution of 1:200 (1 ug/ml). Detection: DAB.

PABPC4 Antibody (aa525-575) LS-C288264
Rabbit Polyclonal (IgG) to Human PABPC4
Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Human
IF IHC IHC-P IP WB
Unconjugated
100µl 0.2mg/ml  $395.00
Detection of Human PABP4 by Immunohistochemistry. Sample: FFPE section of human prostate carcinoma (left) and colon carcinoma (right). Antibody: Affinity purified rabbit anti-PABP4 used at a dilution of 1:200 (1 ug/ml). Detection: DAB.
Detection of Human PABP4 by Immunohistochemistry. Sample: FFPE section of human prostate carcinoma (left) and colon carcinoma (right). Antibody: Affinity purified rabbit anti-PABP4 used at a dilution of 1:200 (1 ug/ml). Detection: DAB.

PABPC4 Antibody (aa525-575) LS-C286775
Rabbit Polyclonal (IgG) to Human PABPC4
Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Human
IF IHC IHC-P
Unconjugated
100µl  $415.00
Detection of Human PABP4 by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-PABP4 used at a dilution of 1:250.
Detection of Mouse PABP4 by Immunohistochemistry. Sample: FFPE section of mouse teratoma. Antibody: Affinity purified rabbit anti-PABP4 used at a dilution of 1:250.
Detection of Human PABP4 by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-PABP4 used at a dilution of 1:250.
Detection of Mouse PABP4 by Immunohistochemistry. Sample: FFPE section of mouse teratoma. Antibody: Affinity purified rabbit anti-PABP4 used at a dilution of 1:250.

PABPC4 Antibody LS-C334410
Rabbit Polyclonal (IgG) to Human PABPC4
Mouse, Rat, Human
IHC WB
Unconjugated
50µl  $235.00; 100µl  $295.00; 200µl  $385.00
Immunohistochemistry of paraffin-embedded human esophagus.
Immunohistochemistry of paraffin-embedded mouse brain tissue.
Immunohistochemistry of paraffin-embedded human esophagus.
Immunohistochemistry of paraffin-embedded mouse brain tissue.

PABPC4 Antibody LS-C155691
Rabbit Polyclonal (IgG) to Human PABPC4
Human
IHC IHC-P WB
Unconjugated
100µl 0.6mg/ml  $335.00
IHC of paraffin-embedded CL1-5 xenograft, using PABPC4 antibody antibody at 1:500 dilution.
Sample (30 ug of whole cell lysate) A: 293T 7.5% SDS PAGE PABPC4 antibody diluted at 1:1000
IHC of paraffin-embedded CL1-5 xenograft, using PABPC4 antibody antibody at 1:500 dilution.
Sample (30 ug of whole cell lysate) A: 293T 7.5% SDS PAGE PABPC4 antibody diluted at 1:1000

PABPC4 Antibody (aa181-230) LS-C31358
Rabbit Polyclonal (IgG) to Human PABPC4
Mouse, Dog, Rat, Horse, Bat, Human, Monkey
IHC IHC-P WB
Unconjugated
100µg  $325.00
PABPC4 antibody ARP40496_T100-NP_003810-PABPC4 (poly(A) binding protein, cytoplasmic 4 (inducible form)) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
A: Marker, B: HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
PABPC4 antibody ARP40496_T100-NP_003810-PABPC4 (poly(A) binding protein, cytoplasmic 4 (inducible form)) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
A: Marker, B: HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

PABPC4 Antibody (aa181-230, HRP) LS-C440499
Rabbit Polyclonal (IgG) to Human PABPC4
Mouse, Dog, Rat, Horse, Bat, Gibbon, Chimpanzee, Human, Monkey
IHC IHC-P WB
HRP Conjugated
100µl 0.65mg/ml  $335.00
PABPC4 antibody ARP40496_T100-NP_003810-PABPC4 (poly(A) binding protein, cytoplasmic 4 (inducible form)) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
A: Marker, B: HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
PABPC4 antibody ARP40496_T100-NP_003810-PABPC4 (poly(A) binding protein, cytoplasmic 4 (inducible form)) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
A: Marker, B: HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

PABPC4 Antibody (aa181-230, Biotin) LS-C440497
Rabbit Polyclonal (IgG) to Human PABPC4
Mouse, Dog, Rat, Horse, Bat, Gibbon, Chimpanzee, Human, Monkey
IHC IHC-P WB
Biotin Conjugated
100µl 1mg/ml  $335.00
PABPC4 antibody ARP40496_T100-NP_003810-PABPC4 (poly(A) binding protein, cytoplasmic 4 (inducible form)) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
A: Marker, B: HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
PABPC4 antibody ARP40496_T100-NP_003810-PABPC4 (poly(A) binding protein, cytoplasmic 4 (inducible form)) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
A: Marker, B: HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

PABPC4 Antibody (aa181-230, FITC) LS-C440500
Rabbit Polyclonal (IgG) to Human PABPC4
Mouse, Dog, Rat, Horse, Bat, Gibbon, Chimpanzee, Human, Monkey
IHC IHC-P WB
FITC Conjugated
100µl 1mg/ml  $335.00
PABPC4 antibody ARP40496_T100-NP_003810-PABPC4 (poly(A) binding protein, cytoplasmic 4 (inducible form)) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
A: Marker, B: HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
PABPC4 antibody ARP40496_T100-NP_003810-PABPC4 (poly(A) binding protein, cytoplasmic 4 (inducible form)) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
A: Marker, B: HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

PABPC4 Antibody LS-C668170
Rabbit Polyclonal to Human PABPC4
Human
IHC IHC-P WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $275.00
Immunohistochemistry - Paraffin Image
Western blot Image
Immunohistochemistry - Paraffin Image
Western blot Image

PABPC4 Antibody (Internal) LS-C144926
Rabbit Polyclonal to Human PABPC4
Human
IHC WB
Unconjugated
100µl  $365.00

PABPC4 Antibody (aa219-247) LS-C323749
Rabbit Polyclonal (IgG) to Human PABPC4
Human
ELISA WB
Unconjugated
200µl  $530.00

PABPC4 Antibody (aa219-247, Biotin) LS-C265427
Rabbit Polyclonal (IgG) to Human PABPC4
Human
ELISA WB
Biotin Conjugated
200µl  $680.00

PABPC4 Antibody (aa219-247, FITC) LS-C265428
Rabbit Polyclonal (IgG) to Human PABPC4
Human
ELISA WB
FITC Conjugated
200µl  $680.00

PABPC4 Antibody (aa219-247, AP) LS-C265425
Rabbit Polyclonal (IgG) to Human PABPC4
Human
ELISA WB
AP Conjugated
200µl  $680.00

PABPC4 Antibody (aa219-247, APC) LS-C265426
Rabbit Polyclonal (IgG) to Human PABPC4
Human
ELISA WB
APC Conjugated
200µl  $680.00

PABPC4 Antibody (aa219-247, Azide-free, HRP) LS-C265429
Rabbit Polyclonal (IgG) to Human PABPC4
Human
ELISA WB
HRP Conjugated, Azide-free
200µl  $680.00

PABPC4 Antibody (aa219-247, PE) LS-C265430
Rabbit Polyclonal (IgG) to Human PABPC4
Human
ELISA WB
PE Conjugated
200µl  $680.00

PABPC4 Antibody (aa219-247) LS-C158520
Rabbit Polyclonal to Human PABPC4
Human
WB
Unconjugated
400µl  $305.00
PABPC4 Antibody western blot of U937 cell line lysates (35 ug/lane). The PABPC4 antibody detected the PABPC4 protein (arrow).
PABPC4 Antibody western blot of U937 cell line lysates (35 ug/lane). The PABPC4 antibody detected the PABPC4 protein (arrow).

PABPC4 Antibody (aa432-481) LS-C80344
Rabbit Polyclonal (IgG) to Human PABPC4
Rabbit, Guinea pig, Rat, Horse, Human, Monkey
WB
Unconjugated
50µg  $365.00
HepG2 cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

PABPC4 Antibody (aa432-481, HRP) LS-C440498
Rabbit Polyclonal (IgG) to Human PABPC4
Rabbit, Guinea pig, Rat, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
HepG2 cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

PABPC4 Antibody (aa432-481, Biotin) LS-C440495
Rabbit Polyclonal (IgG) to Human PABPC4
Rabbit, Guinea pig, Rat, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100µl 1mg/ml  $385.00
HepG2 cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

PABPC4 Antibody (aa432-481, FITC) LS-C440496
Rabbit Polyclonal (IgG) to Human PABPC4
Rabbit, Guinea pig, Rat, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100µl 1mg/ml  $385.00
HepG2 cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Showing 1-24 of 24 results

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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