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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PA / Protective Antigen

protective antigen

Anthrax PA (Protective Antigen) and Anthrax LF (Lethal Factor), along with Anthrax EF (Edema Factor), are toxins produced by Bacillus anthracis. All three of the proteins must be present for toxicity to occur. It begins with the binding of PA to its cell-surface receptor, ATR (Anthrax Toxin Receptor), at which point PA is cleaved and the resulting 63 kD carboxyl-terminal fragment binds to LF and EF. LF is a protease that is known to cleave members of the mitogen-activated protein kinase kinase (MAPKK) family (Cunningham K, Lacy DB, Mogridge J, Collier RJ. Proc Natl Acad Sci U S A. 2002).

Gene Name: protective antigen
Family/Subfamily: Virulence Factor
Synonyms: pagA, PagA, pagA protective antigen, Protective antigen
Target Sequences: NP_652920.1

Filtered by: None
Target
PA / Protective Antigen (87)
Reactivity
Ant (6)
Bacillus (6)
Bacillus anthracis (82)
Bacteria (5)
Application
IHC (2)
WB (51)
ELISA (79)
IP (1)
RIA (1)
Host
rabbit (8)
mouse (75)
goat (2)
chicken (2)
Isotype
IgG (7)
IgG1 (35)
IgG2b (40)
IgY (2)
Clonality
monoclonal mc (75)
polyclonal pc (12)
Clone
101 (1)
102 (1)
105 (1)
106 (1)
1216587 (1)
5216587 (1)
7821 (1)
BAP0101 (1)
BAP0102 (2)
BAP0104 (3)
BAP0105 (1)
BAP0106 (2)
BAPO101 (1)
BAPO102 (1)
BAPO105 (1)
BAPO106 (1)
C3 (4)
PA6 (1)
Format
AP Conjugated (6)
APC Conjugated (5)
Azide-free (2)
Biotin Conjugated (8)
FITC Conjugated (6)
HRP Conjugated (7)
PE Conjugated (6)
Preservative Free (2)
Unconjugated (49)
Epitope
aa186-192 (2)
aa240-254 (2)
C-Terminus (1)
Internal (1)
Publications
No (87)
Showing 1-25 of 87 results

PA / Protective Antigen Antibody LS-C74530
Mouse Monoclonal (IgG1) to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis
ELISA, WB
Unconjugated
500µg  $455.00; 1mg  $755.00

PA / Protective Antigen Antibody (AP) LS-C505586
Mouse Monoclonal (IgG1) to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis
ELISA, WB
AP Conjugated
100µl  $875.00

PA / Protective Antigen Antibody LS-C19484
Rabbit Polyclonal (IgG) to Bacteria PA / Protective Antigen
Bacteria
ELISA
Unconjugated
0.1mg 1mg/ml  $365.00

PA / Protective Antigen Antibody LS-C126958
Goat Polyclonal (IgG) to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis
ELISA, WB
Unconjugated
100µg  $755.00

PA / Protective Antigen Antibody (clone 7821) LS-C58770
Mouse Monoclonal [clone 7821] (IgG2b) to Bacteria PA / Protective Antigen
Bacteria
ELISA
Unconjugated
0.1mg  $530.00

PA / Protective Antigen Antibody (clone 1216587) LS-C195450
Mouse Monoclonal [clone 1216587] (IgG2b) to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis, Bacillus, Ant
ELISA, IHC, WB
Unconjugated
100µg  $385.00

PA / Protective Antigen Antibody (clone 5216587) LS-C195451
Mouse Monoclonal [clone 5216587] (IgG2b) to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis, Bacillus, Ant
ELISA, IHC, WB
Unconjugated
100µg  $385.00

PA / Protective Antigen Antibody (clone BAPO102) LS-C84797
Mouse Monoclonal [clone BAPO102] (IgG2b) to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis
ELISA
Unconjugated
1mg  $495.00

PA / Protective Antigen Antibody LS-C19483
Rabbit Polyclonal (IgG) to Bacteria PA / Protective Antigen
Bacteria
ELISA
Unconjugated
0.1mg 1mg/ml  $365.00

PA / Protective Antigen Antibody (aa186-192) LS-C19423
Rabbit Polyclonal to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis
WB
Unconjugated
200µl  $335.00
Western blot of Anthrax PA in recombinant protein using antibody (Lane B) at 1:1000 dilution. Lane A shows the pre-bleed.

PA / Protective Antigen Antibody (clone BAP0102) LS-C58343
Mouse Monoclonal [clone BAP0102] (IgG2b) to Bacteria PA / Protective Antigen
Bacteria
ELISA, WB
Unconjugated
0.2mg  $405.00

PA / Protective Antigen Antibody (clone PA6) LS-C63075
Mouse Monoclonal [clone PA6] (IgG1) to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis
IP, RIA, WB
Unconjugated
100µg  $355.00

PA / Protective Antigen Antibody LS-C74536
Mouse Monoclonal (IgG2b) to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis
ELISA, WB
Unconjugated
500µg  $455.00; 1mg  $755.00

PA / Protective Antigen Antibody (AP) LS-C505594
Mouse Monoclonal (IgG2b) to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis
ELISA, WB
AP Conjugated
100µl  $875.00

PA / Protective Antigen Antibody LS-C74546
Mouse Monoclonal (IgG1) to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis
ELISA, WB
Unconjugated
500µg  $465.00; 1mg  $785.00

PA / Protective Antigen Antibody (AP) LS-C505595
Mouse Monoclonal (IgG1) to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis
ELISA, WB
AP Conjugated
100µl  $905.00

PA / Protective Antigen Antibody LS-C74547
Mouse Monoclonal (IgG1) to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis
ELISA, WB
Unconjugated
500µg  $465.00; 1mg  $785.00

PA / Protective Antigen Antibody (clone C3) LS-C83209
Mouse Monoclonal [clone C3] (IgG1) to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis
ELISA, WB
Unconjugated
200µg  $305.00

PA / Protective Antigen Antibody (clone 101) LS-C83210
Mouse Monoclonal [clone 101] (IgG2b) to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis
ELISA, WB
Unconjugated
200µg  $305.00

PA / Protective Antigen Antibody (clone 102) LS-C83211
Mouse Monoclonal [clone 102] (IgG2b) to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis
ELISA, WB
Unconjugated
200µg  $305.00

PA / Protective Antigen Antibody (clone 105) LS-C83214
Mouse Monoclonal [clone 105] (IgG1) to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis
ELISA, WB
Unconjugated
200µg  $305.00

PA / Protective Antigen Antibody (clone 106) LS-C83215
Mouse Monoclonal [clone 106] (IgG1) to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis
ELISA, WB
Unconjugated
200µg  $305.00

PA / Protective Antigen Antibody LS-C35100
Mouse Monoclonal (IgG1) to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis
ELISA, WB
Unconjugated
50µg 50µl  $445.00; 100µg  $755.00

PA / Protective Antigen Antibody (clone C3) LS-C58342
Mouse Monoclonal [clone C3] (IgG1) to Bacteria PA / Protective Antigen
Bacteria
ELISA, WB
Unconjugated
0.2mg  $405.00

PA / Protective Antigen Antibody (AP) LS-C505592
Mouse Monoclonal (IgG2b) to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis
ELISA, WB
AP Conjugated
100µl  $770.00
Showing 1-25 of 87 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).