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Services
Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
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PA / Protective Antigen

protective antigen

Anthrax PA (Protective Antigen) and Anthrax LF (Lethal Factor), along with Anthrax EF (Edema Factor), are toxins produced by Bacillus anthracis. All three of the proteins must be present for toxicity to occur. It begins with the binding of PA to its cell-surface receptor, ATR (Anthrax Toxin Receptor), at which point PA is cleaved and the resulting 63 kD carboxyl-terminal fragment binds to LF and EF. LF is a protease that is known to cleave members of the mitogen-activated protein kinase kinase (MAPKK) family (Cunningham K, Lacy DB, Mogridge J, Collier RJ. Proc Natl Acad Sci U S A. 2002).

Gene Name: protective antigen
Family/Subfamily: Virulence Factor
Synonyms: pagA, PagA, pagA protective antigen, Protective antigen
Target Sequences: NP_652920.1

Viewing 1-25 of 77 items
Select
Mouse Monoclonal (IgG1) to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis
ELISA, WB
Unconjugated
500µg   $455.00; 1mg   $755.00
Select
Mouse Monoclonal (IgG1) to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis
ELISA, WB
Biotin Conjugated
100µl   $875.00
Select
Rabbit Polyclonal (IgG) to Bacteria PA / Protective Antigen
Bacteria
ELISA
Unconjugated
0.1mg   1mg/ml   $375.00
Select
Goat Polyclonal (IgG) to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis
ELISA, WB
Unconjugated
100µg   $755.00
Select
Mouse Monoclonal [clone 7821] (IgG2b) to Bacteria PA / Protective Antigen
Bacteria
ELISA
Unconjugated
0.1mg   $545.00
Select
Mouse Monoclonal [clone 5216587] (IgG2b) to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis, Bacillus, Ant
ELISA, IHC, WB
Unconjugated
100µg   $445.00
Select
Mouse Monoclonal [clone 1216587] (IgG2b) to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis, Bacillus, Ant
ELISA, IHC, WB
Unconjugated
100µg   $445.00
Select
Mouse Monoclonal [clone BAPO102] (IgG2b) to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis
ELISA
Unconjugated
1mg   $495.00
Select
Rabbit Polyclonal (IgG) to Bacteria PA / Protective Antigen
Bacteria
ELISA
Unconjugated
0.1mg   1mg/ml   $375.00
PA / Protective Antigen Antibody - Western blot of Anthrax PA in recombinant protein using antibody (Lane B) at 1:1000 dilution. Lane A shows the pre-bleed.
Select
Rabbit Polyclonal to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis
WB
Unconjugated
200µl   $335.00
Select
Mouse Monoclonal [clone C3] (IgG1) to Bacteria PA / Protective Antigen
Bacteria
ELISA, WB
Unconjugated
0.2mg   $405.00
Select
Mouse Monoclonal [clone BAP0102] (IgG2b) to Bacteria PA / Protective Antigen
Bacteria
ELISA, WB
Unconjugated
0.2mg   $405.00
Select
Mouse Monoclonal (IgG1) to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis
ELISA, WB
Unconjugated
100µg   $755.00
Select
Mouse Monoclonal [clone C3] (IgG1) to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis
ELISA, WB
Unconjugated
200µg   $315.00
Select
Mouse Monoclonal [clone 101] (IgG2b) to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis
ELISA, WB
Unconjugated
200µg   $315.00
Select
Mouse Monoclonal [clone 102] (IgG2b) to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis
ELISA, WB
Unconjugated
200µg   $315.00
Select
Mouse Monoclonal [clone 105] (IgG1) to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis
ELISA, WB
Unconjugated
200µg   $315.00
Select
Mouse Monoclonal [clone 106] (IgG1) to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis
ELISA, WB
Unconjugated
200µg   $315.00
Select
Mouse Monoclonal [clone PA6] (IgG1) to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis
IP, RIA, WB
Unconjugated
100µg   $375.00
Select
Mouse Monoclonal (IgG1) to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis
ELISA, WB
Unconjugated
500µg   $465.00; 1mg   $785.00
Select
Mouse Monoclonal (IgG1) to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis
ELISA, WB
Biotin Conjugated
100µl   $905.00
Select
Mouse Monoclonal (IgG1) to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis
ELISA, WB
Unconjugated
500µg   $465.00; 1mg   $785.00
Select
Mouse Monoclonal (IgG1) to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis
ELISA, WB
Biotin Conjugated
100µl   $905.00
Select
Mouse Monoclonal (IgG2b) to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis
ELISA, WB
Unconjugated
500µg   $455.00; 1mg   $755.00
PA / Protective Antigen Antibody - Standard Curve for Anthrax Protective Antigen:Capture Antibody Mouse mAb 201240 to Anthrax Protective Antigen at 4µg/ml and other antibody for detecting.
Select
Mouse Monoclonal (IgG2b) to Bacillus anthracis PA / Protective Antigen
Bacillus anthracis
ELISA, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00

Viewing 1-25 of 77 items


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).