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P4HA2

prolyl 4-hydroxylase, alpha polypeptide II

P4HA2 is a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene Name: prolyl 4-hydroxylase, alpha polypeptide II
Synonyms: P4HA2, 4-PH alpha 2, 4-PH alpha-2, C-P4Halpha(II), p4HA2
Target Sequences: NM_004199 NP_004190.1 O15460

Publications (1)

1
Cancer associated fibroblasts (CAFs) are activated in cutaneous basal cell carcinoma and in the peritumoural skin. Omland SH, Wettergren EE, Mollerup S, Asplund M, Mourier T, Hansen AJ, Gniadecki R. BMC cancer. 2017 17:675. (IHC, ELISA; Human) [Full Text Article] [PubMed:28987144] [PMC:PMC5806272]

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Products
Antibodies (19)
Primary (19)
P4HA2 (19)
Human (19)
Mouse (4)
Rat (4)
Bat (3)
Bovine (3)
Dog (3)
Gibbon (3)
Guinea pig (3)
Horse (3)
Monkey (3)
Rabbit (3)
IHC (4)
IHC-P (2)
WB (18)
ELISA (3)
IP (2)
Peptide-ELISA (1)
rabbit (19)
IgG (6)
polyclonal pc (19)
APC (1)
APC Conjugated (1)
Biotin Conjugated (2)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Preservative Free (1)
Unconjugated (9)
aa207-520 (8)
aa289-338 (4)
aa236-535 (2)
aa250-300 (1)
No (19)
P4HA2 Antibody - P4HA2 antibody Western blot of HepG2 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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P4HA2 Rabbit anti-Human Polyclonal (aa289-338) Antibody
Human
WB
Unconjugated
100 µl/$424
P4HA2 Antibody - P4HA2 antibody Western blot of HepG2 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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P4HA2 Rabbit anti-Human Polyclonal (aa289-338) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Bat, Gibbon, Human, Monkey
WB
HRP Conjugated
100 µl/$469
P4HA2 Antibody - P4HA2 antibody Western blot of HepG2 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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P4HA2 Rabbit anti-Human Polyclonal (aa289-338) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Bat, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
P4HA2 Antibody - P4HA2 antibody Western blot of HepG2 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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P4HA2 Rabbit anti-Human Polyclonal (aa289-338) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Bat, Gibbon, Human, Monkey
WB
FITC Conjugated
100 µl/$469
P4HA2 Antibody - Immunohistochemistry of paraffin-embedded human breast cancer using antibody at 1:100 dilution.
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P4HA2 Rabbit anti-Human Polyclonal (aa236-535) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
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P4HA2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$331
P4HA2 Antibody - Immunohistochemistry of paraffin-embedded human breast cancer using antibody at 1:100 dilution.
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P4HA2 Rabbit anti-Human Polyclonal (aa236-535) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
P4HA2 Antibody - 1:100 staining human pancreas carcinoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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P4HA2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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P4HA2 Rabbit anti-Human Polyclonal (aa250-300) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
P4HA2 Antibody
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P4HA2 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321
P4HA2 Antibody - Anti-P4HA2 rabbit polyclonal antibody at 1:2000 dilution. Lane A: U251 MG Whole Cell Lysate. Lane B: HeLa Whole Cell Lysate. Lane C: H1299 Whole Cell Lysate. Lysates/proteins at 30 ug per lane. Secondary: Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size: 61 kDa.
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P4HA2 Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
WB
Unconjugated, Preservative Free
100 µl/$412
P4HA2 Antibody - Western blot of P4HA2 antibody.
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P4HA2 Rabbit anti-Human Polyclonal (aa207-520) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
P4HA2 Antibody - Western blot of P4HA2 antibody.
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P4HA2 Rabbit anti-Human Polyclonal (aa207-520) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593
P4HA2 Antibody - Western blot of P4HA2 antibody.
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P4HA2 Rabbit anti-Human Polyclonal (aa207-520) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
P4HA2 Antibody - Western blot of P4HA2 antibody.
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P4HA2 Rabbit anti-Human Polyclonal (aa207-520) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716
P4HA2 Antibody - Western blot of P4HA2 antibody.
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P4HA2 Rabbit anti-Human Polyclonal (aa207-520) (Cy3) Antibody
Human
WB
Cy3 Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
P4HA2 Antibody - Western blot of P4HA2 antibody.
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P4HA2 Rabbit anti-Human Polyclonal (aa207-520) (APC) Antibody
Human
WB
APC Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
P4HA2 Antibody - Western blot of P4HA2 antibody.
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P4HA2 Rabbit anti-Human Polyclonal (aa207-520) (APC, Cy7) Antibody
Human
WB
APC, Cy7 Conjugated
100 µl/$505; 200 µl/$648; 500 µl/$1,152; 1 ml/$1,401; 2 ml/$1,961; 5 ml/$3,676
P4HA2 Antibody - Western blot of P4HA2 antibody.
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P4HA2 Rabbit anti-Human Polyclonal (aa207-520) (PE) Antibody
Human
WB
PE Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).