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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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20700 44th Avenue W
Lynnwood, WA 98036
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P450SCC / CYP11A1
cytochrome P450, family 11, subfamily A, polypeptide 1
P450SCC / CYP11A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide.
| Gene Name: | cytochrome P450, family 11, subfamily A, polypeptide 1 |
| Family/Subfamily: | Cytochrome P450 , not assigned-Cytochrome P450 |
| Synonyms: | CYP11A1, Cholesterol 20-22 desmolase, Cholesterol desmolase, Cytochrome P450 11A1, Cytochrome P450C11A1, CYP11A, Cytochrome P450(scc), p450SCC, Steroid 20-22-lyase, CYPXIA1 |
| Target Sequences: | NM_000781 NP_000772.2 P05108 |
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