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P2RY14 / GPR105

purinergic receptor P2Y, G-protein coupled, 14

P2RY14 / GPR105 belongs to the family of G-protein coupled receptors, which contains several receptor subtypes with different pharmacological selectivity for various adenosine and uridine nucleotides. This receptor is a P2Y purinergic receptor for UDP-glucose and other UDP-sugars coupled to G-proteins. It has been implicated in extending the known immune system functions of P2Y receptors by participating in the regulation of the stem cell compartment, and it may also play a role in neuroimmune function. Two transcript variants encoding the same protein have been identified for this gene.

Gene Name: purinergic receptor P2Y, G-protein coupled, 14
Family/Subfamily: GPCR , Sugar sensing
Synonyms: P2RY14, G-protein coupled receptor 105, p2Y purinoceptor 14, p2Y(14) receptor, p2Y14 receptor, UDP-glucose receptor, p2Y14, VTR 15-20 receptor, G protein-coupled receptor 105, GPR105, KIAA0001, p2RY14
Target Sequences: NM_014879 NP_055694.3 Q15391

Publications (3)

1
Time-of-day-dependent expression of purinergic receptors in mouse suprachiasmatic nucleus. Lommen J, Stahr A, Ingenwerth M, Ali AAH, von Gall C. Cell and tissue research. 2017 (IHC, WB; Mouse, Human) [Full Text Article] [PubMed:28547658] [PMC:PMC5579179] Related Antibodies: LS-C120603.
2
Analysis of Spatial and Temporal Distribution of Purinergic P2 Receptors in the Mouse Hippocampus. Julian Lommen, Julika Detken, Katharina Harr, Charlotte von Gall, Amira A H Ali. International journal of molecular sciences. 2021 Jul;22:8078. [Full Text Article] [PubMed:34360844] [PMC:PMC8348931] Related Antibodies: LS-C120603.
3
Expression of the pro-inflammatory P2Y14 receptor in the non-vasectomized and vasectomized human epididymis. Larissa Berloffa Belardin, Christine Légaré, Robert Sullivan, Clémence Belleannée, Sylvie Breton. Andrology. 2022 November;10:1522-1539. [Full Text Article] [PubMed:36029226] Related Antibodies: LS-A1486.

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Proteins (7)
Over-Expression Lysate (4)
Recombinant (3)
P2RY14 / GPR105 (7)
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GST (1)
GST, N-terminus (1)
His-T7 (1)
Myc-DDK (Flag) (4)
Human (5)
293T Cells (2)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
P2RY14 / GPR105 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
P2RY14 / GPR105 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
38.8 kDa
20 µg/$150
P2RY14 / GPR105 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
38.8 kDa
20 µg/$150
P2RY14 / GPR105 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
38.8 kDa
100 µg/$494
P2RY14 / GPR105 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
38.8 kDa
100 µg/$494
P2RY14 / GPR105 Protein - Recombinant Purinergic Receptor P2Y, G Protein Coupled 14 By SDS-PAGE
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E. coli
His-T7
33.0 kDa
10 µg/$285; 50 µg/$470; 100 µg/$750; 200 µg/$937; 1 mg/$2,063; 500 µg/$1,594; 5 mg/$3,277; 2 mg/$2,252
P2RY14 / GPR105 Protein - 12.5% SDS-PAGE of human P2RY14 stained with Coomassie Blue
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Wheat Germ Extract
GST
65.4 kDa
2 µg/$439
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).