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P2RY11 / P2Y11

purinergic receptor P2Y, G-protein coupled, 11

P2RY11 / P2Y11 belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is coupled to the stimulation of the phosphoinositide and adenylyl cyclase pathways and behaves as a selective purinoceptor. Naturally occuring read-through transcripts, resulting from intergenic splicing between this gene and an immediately upstream gene (PPAN, encoding peter pan homolog), have been found. The PPAN-P2RY11 read-through mRNA is ubiquitously expressed and encodes a fusion protein that shares identity with each individual gene product.

Gene Name: purinergic receptor P2Y, G-protein coupled, 11
Family/Subfamily: GPCR , Purinergic
Synonyms: P2RY11, p2RY11, p2Y11, Purinergic receptor P2Y11, p2Y purinoceptor 11
Target Sequences: NM_002566 NP_002557.2 Q96G91

Publications (1)

1
ß-Nicotinamide Adenine Dinucleotide (ß-NAD) Inhibits ATP-Dependent IL-1ß Release from Human Monocytic Cells. Hiller SD, Heldmann S, Richter K, Jurastow I, Küllmar M, Hecker A, Wilker S, Fuchs-Moll G, Manzini I, Schmalzing G, Kummer W, Padberg W, McIntosh JM, Damm J, Zakrzewicz A, Grau V. International journal of molecular sciences. 2018 April;19:pii: E1126. (Human) [Full Text Article] [PubMed:29642561] [PMC:PMC5979475] Related Antibodies: LS-B11662.

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P2RY11 / P2Y11 (1)
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P2RY11 / P2Y11 Protein - 12.5% SDS-PAGE of human P2RY11 stained with Coomassie Blue
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Wheat Germ Extract
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66.44 kDa
2 µg/$439
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).