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P2RX4 / P2X4
purinergic receptor P2X, ligand-gated ion channel, 4
P2RX4 / P2X4 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with high calcium permeability. The main pharmacological distinction between the members of the purinoceptor family is the relative sensitivity to the antagonists suramin and PPADS. The product of this gene has the lowest sensitivity for these antagonists. Multiple alternatively spliced transcript variants, some protein-coding and some not protein-coding, have been found for this gene.
| Gene Name: | purinergic receptor P2X, ligand-gated ion channel, 4 |
| Family/Subfamily: | Ion Channel , P2X receptor |
| Synonyms: | P2RX4, ATP receptor, p2X purinoceptor 4, p2X4R, p2RX4, p2X receptor 4, p2X4, p2X4 purinoceptor, Purinergic receptor P2X4, Purinoceptor P2X4, Purinergic receptor, p2X receptor, subunit 4 |
| Target Sequences: | NM_002560 NP_002551.2 Q99571 |
Publications (3)
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