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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.
TCR Screening ServicesTest your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
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P2RX4 / P2X4
purinergic receptor P2X, ligand-gated ion channel, 4
P2RX4 / P2X4 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with high calcium permeability. The main pharmacological distinction between the members of the purinoceptor family is the relative sensitivity to the antagonists suramin and PPADS. The product of this gene has the lowest sensitivity for these antagonists. Multiple alternatively spliced transcript variants, some protein-coding and some not protein-coding, have been found for this gene.
| Gene Name: | purinergic receptor P2X, ligand-gated ion channel, 4 |
| Family/Subfamily: | Ion Channel , P2X receptor |
| Synonyms: | P2RX4, ATP receptor, p2X purinoceptor 4, p2X4R, p2RX4, p2X receptor 4, p2X4, p2X4 purinoceptor, Purinergic receptor P2X4, Purinoceptor P2X4, Purinergic receptor, p2X receptor, subunit 4 |
| Target Sequences: | NM_002560 NP_002551.2 Q99571 |
Publications (2)
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