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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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P2RX4 / P2X4

purinergic receptor P2X, ligand-gated ion channel, 4

P2RX4 / P2X4 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with high calcium permeability. The main pharmacological distinction between the members of the purinoceptor family is the relative sensitivity to the antagonists suramin and PPADS. The product of this gene has the lowest sensitivity for these antagonists. Multiple alternatively spliced transcript variants, some protein-coding and some not protein-coding, have been found for this gene.

Gene Name: purinergic receptor P2X, ligand-gated ion channel, 4
Family/Subfamily: Ion Channel , P2X receptor
Synonyms: P2RX4, ATP receptor, p2X purinoceptor 4, p2X4R, p2RX4, p2X receptor 4, p2X4, p2X4 purinoceptor, Purinergic receptor P2X4, Purinoceptor P2X4, Purinergic receptor, p2X receptor, subunit 4
Target Sequences: NM_002560 NP_002551.2 Q99571

Publications (2)

1
Role of mast cell activation in inducing microglial cells to release neurotrophin. Yuan H, Zhu X, Zhou S, Chen Q, Zhu X, Ma X, He X, Tian M, Shi X. Journal of neuroscience research. 2010 88:1348-54. [PubMed:20025063] Related Antibodies: LS-C112758.
2
Regenerative protein thymosin beta-4 is a novel regulator of purinergic signaling. Freeman KW, Bowman BR, Zetter BR. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2011 25:907-15. [PubMed:21106936] Related Antibodies: LS-C112758.

Viewing 1-16 of 16 items
P2RX4 / P2X4 Antibody - Anti-P2RX4 / P2X4 antibody IHC staining of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
Goat Polyclonal to Mouse P2RX4 / P2X4
Mouse, Dog, Rat, Hamster, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µg   0.5mg/ml   $425.00
P2RX4 / P2X4 Antibody - Immunohistochemistry of paraffin-embedded human placenta tissue using P2RX4 Antibody at dilution of 1:100
Select
Rabbit Polyclonal (IgG) to Human P2RX4 / P2X4
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50µg   3mg/ml   $285.00; 100µg   3mg/ml   $305.00
Select
Rabbit Polyclonal (IgG) to Human P2RX4 / P2X4
Human
ELISA
HRP Conjugated
50µg   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Human P2RX4 / P2X4
Human
ELISA
Biotin Conjugated
50µg   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Human P2RX4 / P2X4
Human
ELISA
FITC Conjugated
50µg   $285.00; 100µg   $385.00
P2RX4 / P2X4 Antibody - P2RX4 antibody (0.3 ug/ml) staining of Human Kidney lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Select
(2) Publication(s)
Goat Polyclonal to Human P2RX4 / P2X4
Bovine, Pig, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100µg   0.5mg/ml   $405.00
P2RX4 / P2X4 Antibody - Immunofluorescence analysis of U2OS cells.
Select
Rabbit Polyclonal (IgG) to Human P2RX4 / P2X4
Mouse, Human
IF, IHC, WB
Unconjugated
50µl   $235.00; 100µl   $315.00; 200µl   $425.00
Select
Rabbit Polyclonal (IgG) to Human P2RX4 / P2X4
Human
ELISA, Flo, IF, IHC, IP, WB
Unconjugated
100µg   $335.00
P2RX4 / P2X4 Antibody - P2RX4 / P2X4 antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human P2RX4 / P2X4
Chicken, Zebrafish, Guinea pig, Bovine, Human, Monkey
WB
Unconjugated
100µl   0.5mg/ml   $365.00
P2RX4 / P2X4 Antibody - P2RX4 / P2X4 antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human P2RX4 / P2X4
Chicken, Zebrafish, Guinea pig, Bovine, Human, Monkey, Chimpanzee, Gibbon
WB
HRP Conjugated
100µl   0.65mg/ml   $385.00
P2RX4 / P2X4 Antibody - P2RX4 / P2X4 antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human P2RX4 / P2X4
Chicken, Zebrafish, Guinea pig, Bovine, Human, Monkey, Chimpanzee, Gibbon
WB
Biotin Conjugated
100µl   1mg/ml   $385.00
P2RX4 / P2X4 Antibody - P2RX4 / P2X4 antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human P2RX4 / P2X4
Chicken, Zebrafish, Guinea pig, Bovine, Human, Monkey, Chimpanzee, Gibbon
WB
FITC Conjugated
100µl   1mg/ml   $385.00
Select
Rabbit Polyclonal (IgG) to Human P2RX4 / P2X4
Mouse, Human
IF, WB
Unconjugated
60µl   1mg/ml   $235.00; 120µl   1mg/ml   $295.00; 200µl   1mg/ml   $395.00
Select
Rabbit Polyclonal to Human P2RX4 / P2X4
Mouse, Rat, Human
ELISA, WB
Unconjugated
100µg   100µl   1mg/ml   $305.00
Select
Rabbit Polyclonal (IgG) to Rat P2RX4 / P2X4
Rat
ELISA, WB
Unconjugated
50µl   $695.00
P2RX4 / P2X4 Antibody - P2RX4 antibody Western blot. All lanes: Anti P2RX4 at 0.5 ug/ml. WB: Recombinant Human P2RX4 Protein 0.5ng. Predicted band size: 39 kD. Observed band size: 39 kD.
Select
Rabbit Polyclonal to Human P2RX4 / P2X4
Human
WB
Unconjugated
100µg   200µl   0.5mg/ml   $325.00

Viewing 1-16 of 16 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).