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OVOL2

ovo-like zinc finger 2

Zinc-finger transcription repressor factor. Plays a critical role to maintain the identity of epithelial lineages by suppressing epithelial-to mesenchymal transition mainly through the up-regulation of ZEB1 expression. Positively regulates neuronal differentiation By similarity. Suppresses cell cycling and terminal differentiation of keratinocytes by directly repressing MYC and NOTCH1.

Gene Name:	ovo-like zinc finger 2
Synonyms:	OVOL2, BA504H3.3, EUROIMAGE566589, HOvo2, ZNF339, Ovo-like 2 (Drosophila), Zinc finger protein 339
Target Sequences:	NM_021220 NP_067043.2 Q9BRP0

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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