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OVGP1 / Oviductin is a large, carbohydrate-rich, epithelial glycoprotein with numerous O-glycosylation sites located within threonine, serine, and proline-rich tandem repeats. The gene is similar to members of the mucin and the glycosyl hydrolase 18 gene families. Regulation of expression may be estrogen-dependent. Gene expression and protein secretion occur during late follicular development through early cleavage-stage embryonic development. The protein is secreted from non-ciliated oviductal epithelial cells and associates with ovulated oocytes, blastomeres, and spermatozoan acrosomal regions.
Gene Name: | oviductal glycoprotein 1, 120kDa |
Synonyms: | OVGP1, CHIT5, EGP, MUC9, Oviductal glycoprotein, Mucin 9, OGP, Oviduct-specific glycoprotein, Oviductin, Mucin-9, Oviduct glycoprotein |
Target Sequences: | NM_002557 NP_002548.3 Q12889 |
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