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OTUD5

OTU domain containing 5

OTUD5 is a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene Name: OTU domain containing 5
Synonyms: OTUD5, Deubiquitinating enzyme A, Deubiquinating enzyme A, DUBA, OTU domain containing 5
Target Sequences: Q96G74 Q96G74

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Products
Proteins (10)
Over-Expression Lysate (8)
Recombinant (2)
OTUD5 (10)
No (10)
GST (1)
Myc-DDK (Flag) (9)
Human (6)
293T Cells (4)
HEK 293 Cells (5)
Wheat Germ Extract (1)
Purified (1)
OTUD5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
60 kDa
20 µg/$150
OTUD5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
60 kDa
20 µg/$150
OTUD5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
39 kDa
20 µg/$150
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293T Cells
Myc-DDK (Flag)
60.4 kDa
20 µg/$150
OTUD5 Protein - 12.5% SDS-PAGE of human OTUD5 stained with Coomassie Blue
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Wheat Germ Extract
GST
84.4 kDa
10 µg/$479; 25 µg/$670
OTUD5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
60 kDa
100 µg/$494
OTUD5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
60 kDa
100 µg/$494
OTUD5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
39 kDa
100 µg/$494
OTUD5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
60.4 kDa
100 µg/$494
OTUD5 Protein - Purified recombinant protein OTUD5 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
60.4 kDa
20 µg/$1,107
Viewing 1-10 of 10 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).