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Osteonectin / SPARC

secreted protein, acidic, cysteine-rich (osteonectin)

SPARC (secreted protein acidic and rich in cysteine)/Osteonectin is a matricellular glycoprotein that modulates cellular interactions with the ECM and is expressed in tissues undergoing remodeling. It functions as a de-adhesive protein, as a modulator of growth factor activity, and as a cell-cycle inhibitor. It induces changes in endothelial cell shape via F-actin, coincident with the appearance of intercellular gaps, that provide a paracellular pathway for extravasation of macromolecules. Tumor growth is enhanced in mice lacking SPARC due to changes in the ECM that create a more permissive environment for tumor progression.

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Primary (90)

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Osteonectin / SPARC (142)

Reactivity

Human (72)

Mouse (38)

Rat (30)

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Chicken (2)

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Gibbon (3)

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Osteonectin / SPARC Antibody (clone 5031) LS-C25800

(4.0) Rating

(1) Publication(s)

Antibody:

Osteonectin / SPARC Mouse anti-Human Monoclonal (5031) Antibody

Reactivity:

Bovine, Rat, Human

Applications:

ELISA, IHC, RIA, WB

Format:

Unconjugated

Price:

100 µg/$518

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Osteonectin / SPARC Antibody (clone ON1-1) LS-C83590

Antibody:

Osteonectin / SPARC Mouse anti-Bovine Monoclonal (ON1-1) Antibody

Reactivity:

Bovine, Human

Applications:

ELISA, IHC, IHC-Fr, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$567

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Osteonectin / SPARC Antibody (aa1-304, Biotin) LS-C280453

Antibody:

Osteonectin / SPARC Mouse anti-Human Monoclonal (aa1-304) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$904

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Osteonectin / SPARC Antibody (aa224-251) LS-C161424

Antibody:

Osteonectin / SPARC Rabbit anti-Human Polyclonal (aa224-251) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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Rat Osteonectin / SPARC (Sandwich ELISA) ELISA Kit - LS-F23595

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Mouse Osteonectin / SPARC (Sandwich ELISA) ELISA Kit - LS-F21843

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

3.125 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Rat Osteonectin / SPARC Protein (Recombinant His) (aa18-301) - LS-G12836

Source:

E. coli

Tag:

His

Molecular Weight:

33.6 kDa

Price:

10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

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Mouse Osteonectin / SPARC (Sandwich ELISA) ELISA Kit - LS-F4333

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$782

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PathPlus™ Osteonectin / SPARC Antibody (clone 2B1) LS-B13205

Cancer

(5.0) Rating

Antibody:

Osteonectin / SPARC Mouse anti-Human Monoclonal (2B1) Antibody

Reactivity:

Human

Applications:

IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$440

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Human Osteonectin / SPARC (Sandwich ELISA) ELISA Kit - LS-F22075

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.31 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$771

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Osteonectin / SPARC Antibody LS-C331587

Antibody:

Osteonectin / SPARC Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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Osteonectin / SPARC Antibody (Gly53) LS-C191122

Antibody:

Osteonectin / SPARC Rabbit anti-Human Polyclonal (Gly53) Antibody

Reactivity:

Mouse, Human, Monkey

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µl/$688

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Osteonectin / SPARC Antibody LS-C25802

Antibody:

Osteonectin / SPARC Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

100 µl/$826

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Osteonectin / SPARC Antibody (aa224-251, Biotin) LS-C280447

Antibody:

Osteonectin / SPARC Rabbit anti-Human Polyclonal (aa224-251) (Biotin) Antibody

Reactivity:

Human

Applications:

Flo, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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Osteonectin / SPARC Antibody (aa224-251, FITC) LS-C280448

Antibody:

Osteonectin / SPARC Rabbit anti-Human Polyclonal (aa224-251) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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Osteonectin / SPARC Antibody (aa224-251, APC) LS-C280445

Antibody:

Osteonectin / SPARC Rabbit anti-Human Polyclonal (aa224-251) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

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Osteonectin / SPARC Antibody (aa224-251, Azide-free, HRP) LS-C280449

Antibody:

Osteonectin / SPARC Rabbit anti-Human Polyclonal (aa224-251) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Biotin
• FITC
• APC
• HRP, Azide-free

• Biotin
• FITC
• APC
• More...
  • HRP, Azide-free

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Osteonectin / SPARC Antibody LS-C124320

Antibody:

Osteonectin / SPARC Rat anti-Mouse Monoclonal Antibody

Reactivity:

Mouse

Applications:

ELISA, Flo, IHC, IHC-Fr

Format:

Unconjugated

Price:

500 µg/$1,089

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Osteonectin / SPARC Antibody (clone ON1-1) LS-C25804

Antibody:

Osteonectin / SPARC Mouse anti-Bovine Monoclonal (ON1-1) Antibody

Reactivity:

Bovine, Human

Applications:

ELISA, Flo, IHC, WB

Format:

Unconjugated

Price:

100 µg/$860

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Rat Osteonectin / SPARC (Sandwich ELISA) ELISA Kit - LS-F4332

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$818

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Osteonectin / SPARC Antibody (aa18-303) LS-C401048

Antibody:

Osteonectin / SPARC Rabbit anti-Human Polyclonal (aa18-303) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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Osteonectin / SPARC Antibody LS-C131158

Antibody:

Osteonectin / SPARC Goat anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

ELISA, Flo, WB

Format:

Unconjugated

Price:

100 µg/$962

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Osteonectin / SPARC Antibody (aa18-303) LS-C404304

Antibody:

Osteonectin / SPARC Rabbit anti-Human Polyclonal (aa18-303) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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Osteonectin / SPARC Antibody (C-Terminus, HRP) LS-C470656

Antibody:

Osteonectin / SPARC Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Zebrafish, Mouse, Horse, Rat, Orangutan, Gibbon, Human, Monkey, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

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Osteonectin / SPARC Antibody (aa18-273) LS-C314622

Antibody:

Osteonectin / SPARC Guinea pig anti-Rabbit Polyclonal (aa18-273) Antibody

Reactivity:

Rabbit

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206

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