Osteonectin / SPARC

secreted protein, acidic, cysteine-rich (osteonectin)

SPARC (secreted protein acidic and rich in cysteine)/Osteonectin is a matricellular glycoprotein that modulates cellular interactions with the ECM and is expressed in tissues undergoing remodeling. It functions as a de-adhesive protein, as a modulator of growth factor activity, and as a cell-cycle inhibitor. It induces changes in endothelial cell shape via F-actin, coincident with the appearance of intercellular gaps, that provide a paracellular pathway for extravasation of macromolecules. Tumor growth is enhanced in mice lacking SPARC due to changes in the ECM that create a more permissive environment for tumor progression.

☰ Filters

Products

Proteins (20)

Type

Over-Expression Cell Culture Supernatant (1)

Over-Expression Lysate (3)

Recombinant (16)

Target

Osteonectin / SPARC (20)

Publications

No (20)

Tag

6His, C-terminus (3)

6His, N-terminus (1)

8His, N-terminus (1)

GST (2)

His (3)

His, N-Terminal (1)

His,C-terminus (1)

His-T7 (2)

Myc-DDK (Flag) (3)

Species

Human (14)

Mouse (3)

Rabbit (1)

Rat (1)

Source

293T Cells (1)

CHO Cells (1)

E. coli (8)

HEK 293 Cells (5)

Human (1)

Human Cells (1)

Mammalian Cells (2)

Wheat Germ Extract (1)

Purification

Purified (7)

Low Endotoxin Level

Low endotoxin level (6)

Biologically Active

Biologically active (4)

Select

Rat Osteonectin / SPARC Protein (Recombinant His) (aa18-301) - LS-G12836

Source:

E. coli

Tag:

His

Molecular Weight:

33.6 kDa

Price:

10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

Select

Human Osteonectin / SPARC Protein (Recombinant) - LS-G101

Source:

CHO Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

43.7 kDa

Price:

10 µg/$268; 50 µg/$349

Select

Rabbit Osteonectin / SPARC Protein (Recombinant His-T7) (aa18-273) - LS-G12837

Source:

E. coli

Tag:

His-T7

Molecular Weight:

32.8 kDa

Price:

10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257

Select

Osteonectin / SPARC Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117528

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.5 kDa

Price:

100 µg/$494

Select

Human Osteonectin / SPARC Protein (Recombinant) - LS-G145719

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1 EU/µg (determined by LAL method).

Molecular Weight:

36.1 kDa

Price:

1 mg/$1,656; 50 µg/$364

Select

Human Osteonectin / SPARC Protein (Recombinant GST) (Full Length) - LS-G30507

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

59.07 kDa

Price:

10 µg/$479; 25 µg/$670

Select

Human Osteonectin / SPARC Protein (Recombinant GST) (aa18-303) - LS-G22467

Source:

E. coli

Tag:

GST

Molecular Weight:

60.1 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

Select

Human Osteonectin / SPARC Protein (Over-Expression Cell Culture Supernatant 6His, N-terminus) (Ala18-Ile303) - LS-G26853

Source:

HEK 293 Cells

Tag:

6His, N-terminus

Molecular Weight:

35 kDa

Price:

200 µl/$283

Select

Human Osteonectin / SPARC Protein (Over-Expression Lysate 8His, N-terminus) (Ala18-Ile303) - LS-G26710

Source:

HEK 293 Cells

Tag:

8His, N-terminus

Molecular Weight:

35 kDa

Price:

100 µg/$298

Select

Human Osteonectin / SPARC Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67006

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.5 kDa

Price:

20 µg/$1,107

Select

Human Osteonectin / SPARC Protein (Recombinant His, N-Terminal) (Ala18-Ile303) - LS-G96916

Source:

HEK 293 Cells

Tag:

His, N-Terminal

Molecular Weight:

35 kDa (40-45 kDa reducing conditions)

Price:

10 µg/$289; 50 µg/$360

Select

Human Osteonectin / SPARC Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78916

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.5 kDa

Price:

20 µg/$150

Select

Human Osteonectin / SPARC Protein (Recombinant) (aa18-297) - LS-G5573

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

32.7 kDa

Price:

10 µg/$282; 500 µg/$1,058; 100 µg/$503

Select

Human Osteonectin / SPARC Protein (Recombinant His) (aa18-303) - LS-G5577

Source:

E. coli

Tag:

His

Biological Activity:

Biologically active

Molecular Weight:

36.1 kDa

Price:

10 µg/$282; 100 µg/$503; 500 µg/$1,058

Select

Human Osteonectin / SPARC Protein (Recombinant 6His, C-terminus) (Ala18-Ile303) - LS-G138694

Source:

Mammalian Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

33.7 kDa

Price:

10 µg/$248; 50 µg/$311

Select

Mouse Osteonectin / SPARC Protein (Recombinant His,C-terminus) (Ala18-Ile302) - LS-G139373

Source:

Mammalian Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

33.6 kDa

Price:

10 µg/$277; 50 µg/$389

Select

Human Osteonectin / SPARC Protein (Recombinant 6His, C-terminus) (Ala18-Ile303) - LS-G38907

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

33.73kD

Price:

10 µg/$248; 50 µg/$313; 500 µg/$743; 1 mg/$1,048

Select

Mouse Osteonectin / SPARC Protein (Recombinant 6His, C-terminus) (Ala18-Ile302) - LS-G55766

Source:

Human

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

33.6kD

Price:

50 µg/$395; 500 µg/$1,262; 1 mg/$1,627; 10 µg/$277

Select

Human Osteonectin / SPARC Protein (Recombinant His-T7) (aa18-303) - LS-G12833

Source:

E. coli

Tag:

His-T7

Molecular Weight:

36.2 kDa

Price:

10 µg/$260; 50 µg/$335; 100 µg/$497; 200 µg/$622; 1 mg/$1,588; 500 µg/$1,185; 5 mg/$2,522; 2 mg/$1,760

Select

Mouse Osteonectin / SPARC Protein (Recombinant His) (aa18-302) - LS-G12835

Source:

E. coli

Tag:

His

Molecular Weight:

33.8 kDa

Price:

10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

Viewing 1-20 of 20 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

---

Filtered By:

Products: Proteins

Clear Filters

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.