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OSBPL9 encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This family member functions as a cholesterol transfer protein that regulates Golgi structure and function. Multiple transcript variants, most of which encode distinct isoforms, have been identified. Related pseudogenes have been identified on chromosomes 3, 11 and 12.
Gene Name: | oxysterol binding protein-like 9 |
Synonyms: | OSBPL9, ORP-9, ORP9, OSBP-related protein 9, OSBP4 |
Target Sequences: | NM_024586 NP_078862.4 Q96SU4 |
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