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OSBPL3 encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. The encoded protein is involved in the regulation of cell adhesion and organization of the actin cytoskeleton. Alternative splicing results in multiple transcript variants.
Gene Name: | oxysterol binding protein-like 3 |
Synonyms: | OSBPL3, KIAA0704, OSBP-related protein 3, OSBP3, ORP-3, ORP3, Oxysterol-binding protein 3 |
Target Sequences: | NM_015550 NP_056365.1 Q9H4L5 |
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