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ORMDL3
ORM1-like 3 (S. cerevisiae)
Negative regulator of sphingolipid synthesis. May indirectly regulate endoplasmic reticulum-mediated Ca(+2) signaling.
| Gene Name: | ORM1-like 3 (S. cerevisiae) |
| Synonyms: | ORMDL3, ORM1-like 3 (S. cerevisiae), ORM1-like protein 3, ORM1 (S. cerevisiae)-like 3 |
| Target Sequences: | Q8N138 Q8N138 |
Publications (2)
1
ORMDL3 is an inducible lung epithelial gene regulating metalloproteases, chemokines, OAS, and ATF6. Miller M, Tam AB, Cho JY, Doherty TA, Pham A, Khorram N, Rosenthal P, Mueller JL, Hoffman HM, Suzukawa M, Niwa M, Broide DH. Proceedings of the National Academy of Sciences of the United States of America. 2012 109:16648-53.
[PubMed:23011799]
[PMC:PMC3478632]
2
ORMDL3 may participate in the pathogenesis of bronchial epithelial-mesenchymal transition in asthmatic mice with airway remodeling. Qi Cheng, Yunxiao Shang. Molecular medicine reports. 2018 January;17:995-1005. [Full Text Article]
[PubMed:29115563]
Related Antibodies: LS-B9583.
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