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OPRS1 / SIGMAR1

sigma non-opioid intracellular receptor 1

Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Involved in the regulation of different receptors it plays a role in BDNF signaling and EGF signaling. Also regulates ion channels like the potassium channel and could modulate neurotransmitter release. Plays a role in calcium signaling through modulation together with ANK2 of the ITP3R-dependent calcium efflux at the endoplasmic reticulum. Plays a role in several other cell functions including proliferation, survival and death. Originally identified for its ability to bind various psychoactive drugs it is involved in learning processes, memory and mood alteration.

Gene Name: sigma non-opioid intracellular receptor 1
Synonyms: SIGMAR1, HSigmaR1, ALS16, SIG-1R, Sigma 1-type opioid receptor, SR-BP, Opioid receptor, sigma 1, OPRS1, Sigma1-receptor, SR31747-binding protein, SRBP, Sigma1R, SR-BP1, SR31747 binding protein 1
Target Sequences: NM_005866 NP_005857.1 Q99720

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Proteins (6)
Over-Expression Lysate (4)
Recombinant (2)
OPRS1 / SIGMAR1 (6)
No (6)
GST (1)
Myc-DDK (Flag) (5)
Human (4)
293T Cells (2)
HEK 293 Cells (3)
Wheat Germ Extract (1)
Purified (1)
OPRS1 / SIGMAR1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
21.3 kDa
100 µg/$494
OPRS1 / SIGMAR1 Protein - 12.5% SDS-PAGE of human OPRS1 stained with Coomassie Blue
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Wheat Germ Extract
GST
51.5 kDa
2 µg/$439
OPRS1 / SIGMAR1 Protein - Purified recombinant protein SIGMAR1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
24.9 kDa
20 µg/$1,107
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293T Cells
Myc-DDK (Flag)
24.9 kDa
20 µg/$150
OPRS1 / SIGMAR1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
21.3 kDa
20 µg/$150
OPRS1 / SIGMAR1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
24.9 kDa
100 µg/$494
Viewing 1-6 of 6 product results


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Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).