OPG / Osteoprotegerin

tumor necrosis factor receptor superfamily, member 11b

Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis.

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Products

Proteins (19)

Type

Over-Expression Lysate (2)

Recombinant (17)

Target

OPG / Osteoprotegerin (19)

Publications

No (19)

Tag

6His, C-terminus (2)

Fc, C-terminus (3)

GST (1)

His (3)

His, C-Terminal (1)

His,C-terminus (2)

Myc-DDK (Flag) (2)

Species

Human (14)

Mouse (4)

Source

293T Cells (1)

Baculovirus (1)

E. coli (3)

HEK 293 Cells (4)

Human (1)

Human Cells (3)

Mammalian Cells (4)

Wheat Germ Extract (1)

Yeast (1)

Purification

Purified (7)

Low Endotoxin Level

Low endotoxin level (13)

Biologically Active

Biologically active (4)

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Human OPG / Osteoprotegerin Protein (Recombinant) (aa22-194) - LS-G5842

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

19.7 kDa

Price:

10 µg/$282; 100 µg/$503; 500 µg/$1,058

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Human OPG / Osteoprotegerin Protein (Recombinant Fc, C-terminus) (Glu22-Leu201) - LS-G51865

Source:

Human Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

47.2kD

Price:

10 µg/$321; 50 µg/$534; 500 µg/$1,680; 1 mg/$2,353

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Human OPG / Osteoprotegerin Protein (Recombinant 6His, C-terminus) (Glu22-Leu401) - LS-G38853

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

44.65kD

Price:

10 µg/$240; 50 µg/$299; 500 µg/$929; 1 mg/$1,245

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Mouse OPG / Osteoprotegerin Protein (Recombinant His, C-Terminal) (Glu22-Leu401) - LS-G55748

Source:

Human

Tag:

His, C-Terminal

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

45.1kD

Price:

50 µg/$395; 500 µg/$1,262; 1 mg/$1,627; 10 µg/$277

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Human OPG / Osteoprotegerin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81964

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.03 kDa

Price:

20 µg/$150

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Human OPG / Osteoprotegerin Protein (Recombinant His) - LS-G23913

Source:

HEK 293 Cells

Tag:

His

Molecular Weight:

42.4 kDa

Price:

10 µg/$352; 50 µg/$702; 100 µg/$1,042

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Human OPG / Osteoprotegerin Protein (Recombinant GST) (Full Length) - LS-G29575

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

67.54 kDa

Price:

10 µg/$479; 25 µg/$670

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Mouse OPG / Osteoprotegerin Protein (Recombinant) - LS-G137759

Source:

HEK 293 Cells

Tag:

None

Endotoxin Level:

Less than 0.01 ng/µg (determined by LAL method).

Molecular Weight:

The 620 amino acid recombinant protein has a predicted molecular mass of approximately 70.6 kD. The DTT-reduced and non-reduced protein migrate at approximately 100 kD and 200 kD, respectively, by SDS-PAGE. The predicted N-terminal amino acid is Glu.

Price:

10 µg/$268; 25 µg/$306

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Human OPG / Osteoprotegerin Protein (Recombinant Fc, C-terminus) (Glu22-Leu201) - LS-G140424

Source:

Mammalian Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

47.2 kDa

Price:

10 µg/$317; 50 µg/$524

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Mouse OPG / Osteoprotegerin Protein (Recombinant His,C-terminus) (Glu22-Leu401) - LS-G139316

Source:

Mammalian Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

45.1 kDa

Price:

10 µg/$277; 50 µg/$389

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Human OPG / Osteoprotegerin Protein (Recombinant 6His, C-terminus) (Full Length) - LS-G136737

Source:

Mammalian Cells

Tag:

6His, C-terminus

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

44.65 kDa

Price:

50 µg/$327; 10 µg/$250; 1 mg/$1,518; 500 µg/$1,170

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Mouse OPG / Osteoprotegerin Protein (Recombinant Fc, C-terminus) (Met1-Leu401) - LS-G137974

Source:

HEK 293 Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

70.2 kDa

Price:

100 µg/$502

Select

Human OPG / Osteoprotegerin Protein (Recombinant His,C-terminus) (Glu22-Leu401) - LS-G138667

Source:

Mammalian Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

44.65 kDa

Price:

10 µg/$240; 50 µg/$299

Select

Human OPG / Osteoprotegerin Protein (Recombinant) - LS-G131379

Source:

E. coli

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

~20 kDa

Price:

50 µg/$395; 1 mg/$2,041

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Human OPG / Osteoprotegerin Protein (Recombinant His) - LS-G3506

Source:

Baculovirus

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Price:

30 µg/$411; 150 µg/$985; 6 µg/$276

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Human OPG / Osteoprotegerin Protein (Recombinant) (aa22-201) - LS-G5841

Source:

Yeast

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

109.6 kDa

Price:

10 µg/$282; 100 µg/$503; 500 µg/$1,058

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Human OPG / Osteoprotegerin Protein (Recombinant) - LS-G448

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

20.0 kDa

Price:

10 µg/$268; 50 µg/$349

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Human OPG / Osteoprotegerin Protein (Recombinant His) (Met1-Leu401) - LS-G98675

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

45.3 kDa

Price:

100 µg/$532; 1 mg/$2,785

Select

OPG / Osteoprotegerin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117907

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.03 kDa

Price:

100 µg/$494

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