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OBFC1
oligonucleotide/oligosaccharide-binding fold containing 1
Component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites.
| Gene Name: | oligonucleotide/oligosaccharide-binding fold containing 1 |
| Synonyms: | OBFC1, AAF44, AAF-44, BA541N10.2, CST complex subunit STN1, Alpha accessory factor 44, RPA-32, STN1, RP11-541N10.2 |
| Target Sequences: | NM_024928 NP_079204.2 Q9H668 |
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