OAZ1 / OAZ

ornithine decarboxylase antizyme 1

OAZ1 / OAZ belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis; thus, completing the auto-regulatory circuit. This gene encodes antizyme 1, the first member of the antizyme family, that has broad tissue distribution, and negatively regulates intracellular polyamine levels by binding to and targeting ODC for degradation, as well as inhibiting polyamine uptake. Antizyme 1 mRNA contains two potential in-frame AUGs; and studies in rat suggest that alternative use of the two translation initiation sites results in N-terminally distinct protein isoforms with different subcellular localization. Alternatively spliced transcript variants have also been noted for this gene.

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Antibodies (10)

Type

Primary (10)

Target

OAZ1 / OAZ (10)

Reactivity

Human (10)

Mouse (7)

Rat (6)

Application

IHC (7)

IHC-P (4)

WB (5)

ELISA (2)

Peptide-ELISA (3)

Host

rabbit (8)

goat (2)

Isotype

IgG (5)

Clonality

polyclonal pc (10)

Format

Unconjugated (10)

Epitope

Internal Region (1)

N-Terminus (1)

aa120-132 (1)

aa14-63 (1)

aa2-31 (1)

Publications

No (10)

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OAZ1 / OAZ Antibody (aa2-31) LS-C100686

Antibody:

OAZ1 / OAZ Rabbit anti-Human Polyclonal (aa2-31) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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OAZ1 / OAZ Antibody (N-Terminus) LS-C356233

Antibody:

OAZ1 / OAZ Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$299

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OAZ1 / OAZ Antibody LS-C349303

Antibody:

OAZ1 / OAZ Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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OAZ1 / OAZ Antibody LS-C676205

Antibody:

OAZ1 / OAZ Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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OAZ1 / OAZ Antibody (aa14-63) LS-C120185

Antibody:

OAZ1 / OAZ Rabbit anti-Human Polyclonal (aa14-63) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, Peptide-ELISA

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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OAZ1 / OAZ Antibody LS-C824365

Antibody:

OAZ1 / OAZ Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

100 µg/$357

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OAZ1 / OAZ Antibody LS-C834439

Antibody:

OAZ1 / OAZ Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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OAZ1 / OAZ Antibody (aa120-132) LS-C742531

Antibody:

OAZ1 / OAZ Goat anti-Human Polyclonal (aa120-132) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

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OAZ1 / OAZ Antibody LS-C412133

Antibody:

OAZ1 / OAZ Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

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OAZ1 / OAZ Antibody (Internal Region) LS-C742486

Antibody:

OAZ1 / OAZ Goat anti-Human Polyclonal (Internal Region) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA

Format:

Unconjugated

Price:

100 µg/$401

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