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NXF3

nuclear RNA export factor 3

NXF3 is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus.

Gene Name: nuclear RNA export factor 3
Synonyms: NXF3, Nuclear RNA export factor 3, TAPL-3, TAP-like protein 3, TAPL3
Target Sequences: NM_022052 NP_071335.1 Q9H4D5

Publications (1)

1
Prognostic significance of nuclear RNA export factor 3 in hepatocellular carcinoma. Jiang JH, Gao Q, Ke AW, Yu Y, Shi GM, Fan J, Zhou J, Huang XW. Oncology letters. 2014 7:641-646. (IHC; Human) [Full Text Article] [PubMed:24520286] [PMC:PMC3919940] Related Antibodies: LS-C31687.

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Products
Antibodies (22)
Primary (22)
NXF3 (22)
Human (22)
Chimpanzee (6)
Gibbon (3)
Monkey (3)
IHC (12)
IHC-P (8)
WB (17)
ELISA (8)
IF (1)
Peptide-ELISA (4)
rabbit (21)
mouse (1)
IgG (18)
IgG2a,k (1)
monoclonal mc (1)
polyclonal pc (21)
3A9 (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
Unconjugated (13)
N-Terminus (4)
aa1-531 (4)
aa435-484 (4)
50-130 aa, Internal (1)
Asn104 (1)
Internal (1)
aa55-104 (1)
aa71-104 (1)
aa72-121 (1)
No (21)
Yes (1)
NXF3 Antibody - NXF3 antibody ARP40875_T100-NP_071335-NXF3 (nuclear RNA export factor 3) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human heart.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NXF3 Rabbit anti-Human Polyclonal (aa435-484) Antibody
Human
IHC, WB
Unconjugated
100 µl/$397
NXF3 Antibody - NXF3 antibody ARP40875_T100-NP_071335-NXF3 (nuclear RNA export factor 3) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human heart.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NXF3 Rabbit anti-Human Polyclonal (aa435-484) (HRP) Antibody
Human, Monkey, Chimpanzee, Gibbon
IHC, IHC-P, WB
HRP Conjugated
100 µl/$442
NXF3 Antibody - NXF3 antibody ARP40875_T100-NP_071335-NXF3 (nuclear RNA export factor 3) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human heart.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NXF3 Rabbit anti-Human Polyclonal (aa435-484) (Biotin) Antibody
Human, Monkey, Chimpanzee, Gibbon
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$442
NXF3 Antibody - NXF3 antibody ARP40875_T100-NP_071335-NXF3 (nuclear RNA export factor 3) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human heart.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NXF3 Rabbit anti-Human Polyclonal (aa435-484) (FITC) Antibody
Human, Monkey, Chimpanzee, Gibbon
IHC, IHC-P, WB
FITC Conjugated
100 µl/$442
NXF3 Antibody - HepG2 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NXF3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
NXF3 Antibody - HepG2 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NXF3 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Human, Chimpanzee
WB
HRP Conjugated
100 µl/$469
NXF3 Antibody - HepG2 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NXF3 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Human, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
NXF3 Antibody - HepG2 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NXF3 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Human, Chimpanzee
WB
FITC Conjugated
100 µl/$469
NXF3 Antibody - Immunohistochemistry of paraffin-embedded human heart tissue using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NXF3 Rabbit anti-Human Polyclonal (aa1-531) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
NXF3 Antibody - Immunohistochemistry of paraffin-embedded human heart tissue using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NXF3 Rabbit anti-Human Polyclonal (aa1-531) (HRP) Antibody
Human
ELISA, IHC, IHC-P
HRP Conjugated
50 µg/$294; 100 µg/$360
NXF3 Antibody - Immunohistochemistry of paraffin-embedded human heart tissue using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NXF3 Rabbit anti-Human Polyclonal (aa1-531) (Biotin) Antibody
Human
ELISA, IHC, IHC-P
Biotin Conjugated
50 µg/$294; 100 µg/$360
NXF3 Antibody - Immunohistochemistry of paraffin-embedded human heart tissue using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NXF3 Rabbit anti-Human Polyclonal (aa1-531) (FITC) Antibody
Human
ELISA, IHC, IHC-P
FITC Conjugated
50 µg/$294; 100 µg/$360
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NXF3 Rabbit anti-Human Polyclonal (50-130 aa, Internal) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
NXF3 Antibody - Staining MCF-7 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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NXF3 Rabbit anti-Human Polyclonal Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
NXF3 Antibody - Immunohistochemical analysis of NXF3 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected with HRP and DAB as chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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NXF3 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, IHC-P, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
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NXF3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
100 µg/$351
NXF3 Antibody - Western blot of NXF3 (N104) pAb in extracts from MCF-7 cells.
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NXF3 Rabbit anti-Human Polyclonal (Asn104) Antibody
Human
IHC, WB
Unconjugated
50 µl/$321; 100 µl/$403
NXF3 Antibody - Detection limit for recombinant GST tagged NXF3 is 0.3 ng/ml as a capture antibody.
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NXF3 Mouse anti-Human Monoclonal (3A9) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
NXF3 Antibody - Western blot analysis of extracts from MCF-7 cells, using NXF3 antibody.
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NXF3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
NXF3 Antibody - Western blot analysis of lysates from MCF-7 cells, using NXF3 Antibody. The lane on the right is blocked with the synthesized peptide.
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NXF3 Rabbit anti-Human Polyclonal (aa72-121) Antibody
Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
NXF3 Antibody - Western blot analysis of the lysates from HepG2 cells using NXF3 antibody.
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NXF3 Rabbit anti-Human Polyclonal (aa55-104) Antibody
Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
NXF3 Antibody - All lanes: Anti-NXF3 Antibody (N-Term) at 1:2000 dilution. Lane 1: HeLa whole cell lysate. Lane 2: U-87 MG whole cell lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1:10000 dilution. Predicted band size: 60 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
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NXF3 Rabbit anti-Human Polyclonal (aa71-104) Antibody
Human
Peptide-ELISA, WB
Unconjugated
200 µl/$393
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).