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NUT2 / MED10
mediator complex subunit 10
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
| Gene Name: | mediator complex subunit 10 |
| Synonyms: | MED10, Mediator complex subunit 10, TRG20, TRG-20, NUT2, L6, TRG-17 |
| Target Sequences: | NP_115662.2 Q9BTT4 |
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