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NUP85 / Pericentrin 1

nucleoporin 85kDa

Essential component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance. As part of the NPC Nup107-160 subcomplex plays a role in RNA export and in tethering NUP98/Nup98 and NUP153 to the nucleus. The Nup107-160 complex seems to be required for spindle assembly during mitosis. NUP85 is required for membrane clustering of CCL2-activated CCR2. Seems to be involved in CCR2-mediated chemotaxis of monocytes and may link activated CCR2 to the phosphatidyl-inositol 3-kinase-Rac-lammellipodium protrusion cascade.

Gene Name: nucleoporin 85kDa
Synonyms: NUP85, 85 kDa nucleoporin, Frount, Nucleoporin 85kDa, Nucleoporin Nup75, Nucleoporin Nup85, Nup75, PCNT1, Pericentrin-1
Target Sequences: NM_024844 NP_079120.1 Q9BW27

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Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
NUP85 / Pericentrin 1 (6)
No (6)
GST (1)
GST, N-terminus + His, C-terminus (1)
His-T7 (2)
Myc-DDK (Flag) (2)
Human (4)
Mouse (1)
293T Cells (1)
E. coli (3)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
NUP85 / Pericentrin 1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
74.8 kDa
20 µg/$150
NUP85 / Pericentrin 1 Protein
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E. coli
GST, N-terminus + His, C-terminus
102.8 kDa
50 µg/$419
NUP85 / Pericentrin 1 Protein - Recombinant  porin 85kDa By SDS-PAGE
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E. coli
His-T7
30.7 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
NUP85 / Pericentrin 1 Protein - Recombinant  Nucleoporin 85kDa By SDS-PAGE
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E. coli
His-T7
30.9 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
NUP85 / Pericentrin 1 Protein - 12.5% SDS-PAGE of human NUP85 stained with Coomassie Blue
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Wheat Germ Extract
GST
97.9 kDa
10 µg/$479; 25 µg/$670
NUP85 / Pericentrin 1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
74.8 kDa
100 µg/$494
Viewing 1-6 of 6 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).