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NUP214 / CAN

nucleoporin 214kDa

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. This gene is a member of the FG-repeat-containing nucleoporins. The protein encoded by this gene is localized to the cytoplasmic face of the nuclear pore complex where it is required for proper cell cycle progression and nucleocytoplasmic transport. The 3' portion of this gene forms a fusion gene with the DEK gene on chromosome 6 in a t(6,9) translocation associated with acute myeloid leukemia and myelodysplastic syndrome.

Gene Name: nucleoporin 214kDa
Synonyms: NUP214, 214 kDa nucleoporin, CAN, CAN protein, putative oncogene, D9S46E, N214, Nucleoporin 214kD (CAIN), Nucleoporin 214kDa, Nucleoporin Nup214, p250, CAIN, KIAA0023, Protein CAN
Target Sequences: NM_005085 NP_005076.3 P35658

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Proteins (2)
Recombinant (2)
NUP214 / CAN (2)
No (2)
GST, N-terminus (1)
His (1)
Human (1)
Mouse (1)
E. coli (1)
Wheat Germ Extract (1)
NUP214 / CAN Protein - Recombinant Nucleoporin 214kDa By SDS-PAGE
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E. coli
His
33.6 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
NUP214 / CAN Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).