NUDT3

Nudix (nucleoside Diphosphate Linked Moiety X)-type Motif 3

Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate) and [PP]2-InsP4 (bisdiphosphoinositol tetrakisphosphate), suggesting that it may play a role in signal transduction. InsP6 (inositol hexakisphophate) is not a substrate. Acts as a negative regulator of the ERK1/2 pathway. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate.

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Proteins (3)

Type

Recombinant (3)

Target

NUDT3 (3)

Publications

No (3)

Tag

GST (1)

His (1)

Myc-DDK (Flag) (1)

Species

Human (3)

Source

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human NUDT3 Protein (Recombinant GST) (Full Length) - LS-G32542

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

44.66 kDa

Price:

10 µg/$479; 25 µg/$670

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Human NUDT3 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G70553

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

19.3 kDa

Price:

20 µg/$1,107

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Human NUDT3 Protein (Recombinant His) - LS-G1143

Source:

E. coli

Tag:

His

Price:

50 µg/$361; 250 µg/$739; 10 µg/$261

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