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NUDT2

nudix (nucleoside diphosphate linked moiety X)-type motif 2

NUDT2 is a member of the MutT family of nucleotide pyrophosphatases, a subset of the larger NUDIX hydrolase family. The gene product possesses a modification of the MutT sequence motif found in certain nucleotide pyrophosphatases. The enzyme asymmetrically hydrolyzes Ap4A to yield AMP and ATP and is responsible for maintaining the intracellular level of the dinucleotide Ap4A, the function of which has yet to be established. This gene may be a candidate tumor suppressor gene. Alternative splicing has been observed at this locus and four transcript variants, all encoding the same protein, have been identified.

Gene Name: nudix (nucleoside diphosphate linked moiety X)-type motif 2
Synonyms: NUDT2, Ap4A hydrolase 1, Ap4A hydrolase, Ap4Aase, APAH1, Nudix motif 2, Diadenosine tetraphosphatase
Target Sequences: NM_001161 NP_001152.1 P50583

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Products
Proteins (12)
Over-Expression Lysate (6)
Recombinant (6)
NUDT2 (12)
No (12)
GST (1)
GST, N-terminus (1)
His (2)
Myc-DDK (Flag) (8)
Human (9)
293T Cells (3)
E. coli (3)
HEK 293 Cells (5)
Wheat Germ Extract (1)
Purified (4)
NUDT2 Protein - Purified recombinant protein NUDT2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
16.6 kDa
20 µg/$1,107
NUDT2 Protein - Purified recombinant protein NUDT2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
16.6 kDa
20 µg/$1,107
NUDT2 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
GST, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
NUDT2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
16.6 kDa
20 µg/$150
NUDT2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
17.3 kDa
20 µg/$150
Select
293T Cells
Myc-DDK (Flag)
16.6 kDa
20 µg/$150
Select
E. coli
His
18.3 kDa
100 µg/$843
NUDT2 Protein - 12.5% SDS-PAGE of human NUDT2 stained with Coomassie Blue
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Wheat Germ Extract
GST
41.91 kDa
10 µg/$479; 25 µg/$670
NUDT2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
16.6 kDa
100 µg/$494
NUDT2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
17.3 kDa
100 µg/$494
NUDT2 Protein
Select
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
NUDT2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
16.6 kDa
100 µg/$494
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).