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NUDT11
Nudix (nucleoside Diphosphate Linked Moiety X)-type Motif 11
Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate.
| Gene Name: | Nudix (nucleoside Diphosphate Linked Moiety X)-type Motif 11 |
| Synonyms: | NUDT11, APS1, DIPP3beta, DIPP-3-beta, DIPP3-beta, HDIPP3beta, HAps1, Nudix motif 11, ASP1, DIPP3b |
| Target Sequences: | NM_018159 NP_060629.2 Q96G61 |
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